A Conductive polylactic acid/polyaniline porous scaffold via freeze extraction for potential biomedical applications

被引：17
作者：
Abd Razak, Saiful Izwan [1 ,2 ]
Dahli, Farah Nuruljannah [2 ,3 ]
Wahab, Izzati Fatimah [2 ]
Kadir, Mohammed Rafiq Abdul [2 ]
Muhamad, Ida Idayu [1 ,3 ]
Yusof, Abdul Halim Mohd [3 ]
Adeli, Hassan [4 ]
机构：
[1] Univ Teknol Malaysia, IJN UTM Cardiovasc Engn Ctr, Skudai 81310, Johor, Malaysia
[2] Univ Teknol Malaysia, Med Devices & Technol Grp, Fac Biosci & Med Engn, Skudai, Johor, Malaysia
[3] Univ Teknol Malaysia, Fac Chem & Energy Engn, Skudai, Johor, Malaysia
[4] Univ Mazandaran, Dept Chem Engn, Babol Sar, Iran
来源：
SOFT MATERIALS | 2016年 / 14卷 / 02期
关键词：
Conductive scaffold; electrical conductivity; freeze extraction; polylactic acid; polyaniline; scaffold; tissue engineering; PLA SCAFFOLDS; POLY(VINYL ALCOHOL); PHASE-SEPARATION; PORE-SIZE; TISSUE; FABRICATION; POLYANILINE; ACID); POLYMERS; DESIGN;
D O I：
10.1080/1539445X.2016.1149078
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
This paper reports for the first time a simple yet effective method for fabricating a conductive and highly porous scaffold material made up of polylactic acid (PLA) and conducting polyaniline (PANI). The electrical percolation state was successfully obtained at 3 wt% of PANI inclusions and reached a conductivity level of useable tissue engineering applications at 4 wt%. In addition, preliminary bioactivity test results indicated that the protonating agent could form a chelate at the scaffold surface leading to good in-vitro apatite forming ability during biomimetic immersion. This new conductive scaffold has potential as a suitable biomedical material that requires electrical conductivity.
引用
收藏
页码：78 / 86
页数：9
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