A Conductive polylactic acid/polyaniline porous scaffold via freeze extraction for potential biomedical applications

被引：17

作者：

Abd Razak, Saiful Izwan ^{[1
,2
]}

Dahli, Farah Nuruljannah ^{[2
,3
]}

Wahab, Izzati Fatimah ^{[2
]}

Kadir, Mohammed Rafiq Abdul ^{[2
]}

Muhamad, Ida Idayu ^{[1
,3
]}

Yusof, Abdul Halim Mohd ^{[3
]}

Adeli, Hassan ^{[4
]}

机构：

[1] Univ Teknol Malaysia, IJN UTM Cardiovasc Engn Ctr, Skudai 81310, Johor, Malaysia

[2] Univ Teknol Malaysia, Med Devices & Technol Grp, Fac Biosci & Med Engn, Skudai, Johor, Malaysia

[3] Univ Teknol Malaysia, Fac Chem & Energy Engn, Skudai, Johor, Malaysia

[4] Univ Mazandaran, Dept Chem Engn, Babol Sar, Iran

来源：

SOFT MATERIALS | 2016年 / 14卷 / 02期

关键词：

Conductive scaffold; electrical conductivity; freeze extraction; polylactic acid; polyaniline; scaffold; tissue engineering; PLA SCAFFOLDS; POLY(VINYL ALCOHOL); PHASE-SEPARATION; PORE-SIZE; TISSUE; FABRICATION; POLYANILINE; ACID); POLYMERS; DESIGN;

D O I：

10.1080/1539445X.2016.1149078

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

This paper reports for the first time a simple yet effective method for fabricating a conductive and highly porous scaffold material made up of polylactic acid (PLA) and conducting polyaniline (PANI). The electrical percolation state was successfully obtained at 3 wt% of PANI inclusions and reached a conductivity level of useable tissue engineering applications at 4 wt%. In addition, preliminary bioactivity test results indicated that the protonating agent could form a chelate at the scaffold surface leading to good in-vitro apatite forming ability during biomimetic immersion. This new conductive scaffold has potential as a suitable biomedical material that requires electrical conductivity.

引用

页码：78 / 86

页数：9

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