Computational Study of C-H Insertion Reactions with Ethyl Bromodiazoacetate

被引：17

作者：

Bonge, Hanne Therese ^{[1
]}

Hansen, Tore ^{[1
]}

机构：

[1] Univ Oslo, Dept Chem, N-0315 Oslo, Norway

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 2010卷 / 23期

关键词：

Computational chemistry; Insertion; Reaction mechanisms; Carbenoids; Rhodium; RHODIUM CARBENOIDS; DIAZO COMPOUND; ACTIVATION; FUNCTIONALIZATION; MECHANISM;

D O I：

10.1002/ejoc.201000531

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A computational study of C-H insertion reactions between ethyl bromodiazoacetate and three different substrates is presented The mechanism of the C-H insertion is shown to be substrate dependent, the reaction follows either a concerted mechanism or a two-step mechanism in which complete hydride transfer precedes C-C bond formation

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收藏

页码：4355 / 4359

页数：5

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