Focal Takotsubo Cardiomyopathy With High-Dose Interleukin-2 Therapy for Malignant Melanoma

被引：10

作者：

Damodaran, Senthil ^{[1
]}

Mrozek, Ewa ^{[1
]}

Liebner, David ^{[1
]}

Kendra, Kari ^{[1
]}

机构：

[1] Ohio State Univ, Wexner Med Ctr, Div Med Oncol, Columbus, OH 43210 USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2014年 / 12卷 / 12期

关键词：

REVERSIBLE CARDIOMYOPATHY; METASTATIC MELANOMA;

D O I：

10.6004/jnccn.2014.0168

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

High-dose interleukin-2 (IL-2) is an available treatment option for patients with metastatic melanoma or renal cell carcinoma, and is associated with sustained complete and partial responses in a subset of patients. IL-2, however, is not devoid of toxicities, most of which involve the cardiovascular system and manifest as hypotension, arrhythmias, and cardiomyopathy. This report describes an unusual presentation of takotsubo cardiomyopathy in a postmenopausal woman receiving high-dose IL-2 for metastatic melanoma.

引用

页码：1666 / 1670

页数：5

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