Breast cancer detection by Fourier transform infrared spectrometry

被引:53
作者
Meurens, M
Wallon, J
Tong, JS
Noel, H
Haot, J
机构
[1] UNIV CATHOLIQUE LOUVAIN, CLIN ST LUC, SERV ANAT PATHOL, B-1200 BRUSSELS, BELGIUM
[2] ANAP, B-1030 BRUSSELS, BELGIUM
[3] ERASME UNIV HOSP, SERV ANAT PATHOL, B-1070 BRUSSELS, BELGIUM
关键词
infrared spectrometry; Fourier transform; breast cancer; volume density; malignant cells;
D O I
10.1016/0924-2031(95)00030-5
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Fourier transform infrared spectra of 75 biopsies from 55 cases of breast carcinoma were studied in comparison with histo-morphometry, The spectra of carcinomatous tissues are very different from those of normal tissues. There are evident correlations between the intensity of some infrared absorption bands and the volume density of malignant cells measured by optical microscopy [7]. Very high correlation coefficients are observed for phosphate monoester and phosphodiester bands; significant correlation coefficients are also observed for amide I and II bands.
引用
收藏
页码:341 / 346
页数:6
相关论文
共 15 条
  • [1] [Anonymous], PRINCIPLES TECHNIQUE
  • [2] INFRARED CHARACTERIZATION OF NUCLEI ISOLATED FROM NORMAL AND LEUKEMIC (B-CLL) LYMPHOCYTES .3.
    BENEDETTI, E
    PALATRESI, MP
    VERGAMINI, P
    PAPINESCHI, F
    ANDREUCCI, MC
    SPREMOLLA, G
    [J]. APPLIED SPECTROSCOPY, 1986, 40 (01) : 39 - 43
  • [3] VIRAL ONCOGENES
    BISHOP, JM
    [J]. CELL, 1985, 42 (01) : 23 - 38
  • [4] Chalkley HW, 1943, J NATL CANCER I, V4, P47
  • [5] DARNELL J, 1986, MOL CELL BIOL, P1035
  • [6] DETERMINATION OF SUGARS AND ORGANIC-ACIDS IN FRUIT JUICES BY FT MID-IR INVESTIGATION OF DRY EXTRACT
    DUPUY, N
    MEURENS, M
    SOMBRET, B
    LEGRAND, P
    HUVENNE, JP
    [J]. APPLIED SPECTROSCOPY, 1992, 46 (05) : 860 - 863
  • [7] GOUSTIN AS, 1986, CANCER RES, V46, P1015
  • [8] Parker F.S., 1971, APPL INFRARED SPECTR, V1st
  • [9] RIGAS B, 1992, CANCER RES, V52, P84
  • [10] A FOURIER-TRANSFORM INFRARED SPECTROSCOPIC STUDY OF THE PHOSPHOSERINE RESIDUES IN HEN EGG PHOSVITIN AND OVALBUMIN
    SANCHEZRUIZ, JM
    MARTINEZCARRION, M
    [J]. BIOCHEMISTRY, 1988, 27 (09) : 3338 - 3342