Hypoglycaemic and hypolipidaemic action of alcohol extract of Tinospora cordifolia roots in chemical induced diabetes in rats

被引：45
作者：
Prince, PSM [1 ]
Menon, VP [1 ]
机构：
[1] Annamalai Univ, Dept Biochem, Annamalainagar 608002, Tamil Nadu, India
来源：
PHYTOTHERAPY RESEARCH | 2003年 / 17卷 / 04期
关键词：
Tinospora cordifolia; hypoglycaemic; hypolipidaemic; alloxan diabetes; root extract;
D O I：
10.1002/ptr.1130
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The present investigation was undertaken to evaluate the hypoglycaemic and hypolipidaemic effects of an alcohol extract of Tinospora cordifolia roots, an indigenous plant used in Ayurvedic medicine in India. Oral administration of the extract of Tinospora cordifolia (TCREt) roots for 6 weeks resulted in a significant reduction in blood and urine glucose and in lipids in serum and tissues in alloxan diabetic rats. The extract also prevented a decrease in body weight. Thus our study clearly shows that an alcohol TCREt has a hypoglycaemic and hypolipidaemic action. Copyright (C) 2003 John Wiley Sons, Ltd.
引用
收藏
页码：410 / 413
页数：4
相关论文
共 24 条
  • [1] ALBERTI KGM, 1982, BIOCH COMPLICATIONS, V231
  • [2] HYPOGLYCEMIC EFFECT OF ARTEMISIA-HERBA-ALBA .2. EFFECT OF A VALUABLE EXTRACT ON SOME BLOOD PARAMETERS IN DIABETIC ANIMALS
    ALSHAMAONY, L
    ALKHAZRAJI, SM
    TWAIJ, HAA
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 1994, 43 (03) : 167 - 171
  • [3] IMMUNOMODULATING AGENTS OF PLANT-ORIGIN .1. PRELIMINARY SCREENING
    ATAL, CK
    SHARMA, ML
    KAUL, A
    KHAJURIA, A
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 1986, 18 (02) : 133 - 141
  • [4] CHOPRA RN, 1958, INDIGENOUS DRUGS IND, V426
  • [5] Drabkin DL, 1932, J BIOL CHEM, V98, P719
  • [6] EASY COLORIMETRIC MICROMETHOD FOR ROUTINE DETERMINATION OF FREE FATTY-ACIDS IN PLASMA
    FALHOLT, K
    LUND, B
    FALHOLT, W
    [J]. CLINICA CHIMICA ACTA, 1973, 46 (02) : 105 - 111
  • [7] GUPTA SS, 1967, INDIAN J MED RES, V55, P733
  • [8] NADKARNI AK, 1954, INDIAN MAT MED, V1221
  • [9] NOREEN W, 1992, PLANTA MED, V58, P31
  • [10] PEER F, 1989, Indian Journal of Veterinary Medicine, V9, P154
123