Characterization of high virulent strains of equine rhinopneumonitis virus

被引：0

作者：

Alexeyenkova, S., V ^{[1
]}

Yurov, K. P. ^{[1
]}

机构：

[1] Fed Sci Ctr VIEV, Fed State Budget Inst, 24-1 Ryazanskiy Pr, Moscow 109428, Russia

来源：

III INTERNATIONAL SCIENTIFIC CONFERENCE: AGRITECH-III-2020: AGRIBUSINESS, ENVIRONMENTAL ENGINEERING AND BIOTECHNOLOGIES, PTS 1-8 | 2020年 / 548卷

关键词：

NEUROPATHOGENIC STRAINS; POLYMERASE; HORSES;

D O I：

10.1088/1755-1315/548/4/042041

中图分类号：

S2 [农业工程];

学科分类号：

0828 ;

摘要：

This article presents results of screening samples collected from horses during acute outbreaks of abortion and neurological disorders recorded in 2019-2020 in Russia. The signs of disease were characterized by severe hemorrhagic vasculitis. Massive hemorrhages were observed in organs of aborted fetuses and dead horses. Equine herpesvirus type one was isolated in cell culture. Testing to identify genes encoding glycoprotein B and polymerase catalytic subunit of certain viral isolates were carried out. Virus isolated from horses with signs of encephalomyelitis from the Northwest region had a high degree of phylogenetic relationship with the strain "89c25" of equine herpesvirus type one from Japan, 1989. The same virus was found in horses with signs of rhinopneumonia from the Ural region. The virus isolated after equine abortion from the North Caucasus region had a high degree of phylogenetic relationship with the strain "IT19m10" of equine herpesvirus type one from Italy, 2019. It was established that all viral isolates belong to non-neuropathogenic genotype - A2254.

引用

页数：5

共 13 条

[1] Quantification by real-time PCR of the magnitude and duration of leucocyte-associated viraemia in horses infected with neuropathogenic vs. non-neuropathogenic strains of EHV-1 [J].

Allen, G. P. ;

Breathnach, C. C. .

EQUINE VETERINARY JOURNAL, 2006, 38 (03) :252-257

[2] Development of a real-time polymerase chain reaction assay for rapid diagnosis of neuropathogenic strains of equine herpesvirus-1 [J].

Allen, George P. .

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 2007, 19 (01) :69-72

[3] Antemortern detection of latent infection with neuropathogenic strains of equine herpesvirus-1 in horses [J].

Allen, George P. .

AMERICAN JOURNAL OF VETERINARY RESEARCH, 2006, 67 (08) :1401-1405

[4]

BITSCH V, 1971, ACTA VET SCAND, V12, P134

[5] Detection of equine herpesvirus type 1 using a real-time polymerase chain reaction [J].

Diallo, IS ;

Hewitson, G ;

Wright, L ;

Rodwell, BJ ;

Corney, BG .

JOURNAL OF VIROLOGICAL METHODS, 2006, 131 (01) :92-98

[6] Identification of equine herpesvirus 3 (equine coital exanthema virus), equine gammaherpesviruses 2 and 5, equine adenoviruses 1 and 2, equine arteritis virus and equine rhinitis A virus by polymerase chain reaction [J].

Dynon, K ;

Varrasso, A ;

Ficorilli, N ;

Holloway, SA ;

Reubel, GH ;

Li, F ;

Hartley, CA ;

Studdert, MJ ;

Drummer, HE .

AUSTRALIAN VETERINARY JOURNAL, 2001, 79 (10) :695-702

[7] THE EPIDEMIOLOGY OF EQUID HERPESVIRUS ABORTION - A TANTALIZING MYSTERY [J].

MUMFORD, JA .

EQUINE VETERINARY JOURNAL, 1991, 23 (02) :77-78

[8] Analysis of equid herpesvirus 1 strain variation reveals a point mutation of the DNA polymerase strongly associated with neuropathogenic versus nonneuropathogenic disease outbreaks [J].

Nugent, J ;

Birch-Machin, I ;

Smith, KC ;

Mumford, JA ;

Swann, Z ;

Newton, JR ;

Bowden, RJ ;

Allen, GP ;

Davis-Poynter, N .

JOURNAL OF VIROLOGY, 2006, 80 (08) :4047-4060

[9]

van Maanen C, 2001, EQUINE VET J, V33, P191, DOI 10.1111/j.2042-3306.2001.tb00600.x

[10] Comparison of the growth kinetics of neuropathogenic and nonneuropathogenic equid herpesvirus type 1 (EHV-1) strains in cultured murine neuronal cells and the relevance of the D/N752 coding change in DNA polymerase gene (ORF30) [J].

Yamada, Souichi ;

Matsumura, Tomio ;

Tsujimura, Koji ;

Yamaguchi, Tsuyoshi ;

Ohya, Kenji ;

Fukushi, Hideto .

JOURNAL OF VETERINARY MEDICAL SCIENCE, 2008, 70 (05) :505-511

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