Lanthanides (III) polychelates with benzophenone-based resin derivatives and study of their antimicrobial activities

The polymeric ligand (resin) was prepared from 2-hydroxy-4-methoxybenzophenone with 1,3-butane diol in presence of polyphosphoric acid as a catalyst at 160 degrees C for 13 h. The poly[(2- hyd roxy-4- methoxybenzophe none) 1,3-butylene] H(HMBP-1,3-BD) forms, 1:2 metal:ligand chelates with La(III), Pr(III), Nd(III), Sm(III), Gd(III), Tb(III), and Dy(III). The polymeric ligand and its polychelates were characterized on the basis of elemental analyses, electronic spectra, magnetic susceptibilities, thermogravimetric analysis, and NMR and IR spectroscopies results. The molecular weight was determined using number average molecular weight (M-n) by the vapour pressure osmometry (VPO) method. All the polychelates are paramagnetic in nature. The resin and their polychelates were tested for antimicrobial activity against E. coli, B. substilis, and S. aujeus (bacteria) and S. cerevisiae (yeast). It is found that the synthesized polychelates can be used as antibacterial agents.