Bioprinting of Small-Diameter Blood Vessels

被引：55

作者：

Cao, Xia ^{[1
]}

Maharjan, Sushila ^{[1
]}

Ashfaq, Ramla ^{[1
]}

Shin, Jane ^{[1
]}

Zhang, Yu Shrike ^{[1
]}

机构：

[1] Harvard Med Sch, Div Engn Med, Dept Med, Brigham & Womens Hosp, Cambridge, MA 02139 USA

来源：

ENGINEERING | 2021年 / 7卷 / 06期

基金：

美国国家卫生研究院;

关键词：

Bioprinting; Small-diameter blood vessel; Bioink; Vascular engineering; ENDOTHELIAL GROWTH-FACTOR; EXTRACELLULAR-MATRIX; CELL-ADHESION; MECHANICAL-PROPERTIES; CROSS-LINKING; TISSUE; HYDROGELS; SCAFFOLDS; COLLAGEN; CONSTRUCTS;

D O I：

10.1016/j.eng.2020.03.019

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

There has been an increasing demand for bioengineered blood vessels for utilization in both regenerative medicine and drug screening. However, the availability of a true bioengineered vascular graft remains limited. Three-dimensional (3D) bioprinting presents a potential approach for fabricating blood vessels or vascularized tissue constructs of various architectures and sizes for transplantation and regeneration. In this review, we summarize the basic biology of different blood vessels, as well as 3D bioprinting approaches and bioink designs that have been applied to fabricate vascular and vascularized tissue constructs, with a focus on small-diameter blood vessels. (C) 2021 THE AUTHORS. Published by Elsevier LTD on behalf of Chinese Academy of Engineering and Higher Education Press Limited Company.

引用

页码：832 / 844

页数：13

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