Isolation, structure elucidation, and antioxidant evaluation of cydonioside A, an unusual terpenoid from the fruits of Cydonia vulgaris

被引:18
作者
Fiorentino, Antonio [1 ]
D'Abrosca, Brigida [1 ]
Pacifico, Severina [1 ]
Mastellone, Claudio [1 ]
Piccolella, Simona [1 ]
Monaco, Pietro [1 ]
机构
[1] Univ Naples 2, Dipartimento Sci Vita, I-81100 Caserta, Italy
关键词
D O I
10.1002/cbdv.200790088
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A novel terpenoid, cydonioside A (1), was isolated from the fruits of Cydonia vulgaris PERS. Its structure and relative configuration were elucidated on the basis of in-depth spectroscopic analyses, including 2D-NMR experiments as well as MM + calculations. Compound 1 was assayed for its radical-scavenging activity towards the DPPH radical and the superoxide radical anion (O-2(center dot-)), as well as for its overall antioxidant activity, as assessed by the formation of a phosphomolybdenurn complex.
引用
收藏
页码:973 / 979
页数:7
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