Copper-catalyzed aerobic oxidative dehydrogenation for conversion of 2-(alkylthio)-1,4-dihydropyrimidines to 2-(alkylthio)pyrimidines

被引：12
作者：
Nguyen Huu Trong Phan [1 ]
Sohn, Jeong-Hun [1 ]
机构：
[1] Chungnam Natl Univ, Dept Chem, Coll Nat Sci, Taejon 305764, South Korea
来源：
TETRAHEDRON | 2014年 / 70卷 / 43期
关键词：
Aerobic oxidation; Dehydrogenation; Dihydropyrimidine; Pyrimidine; Copper catalyzed oxidation; COUPLING REACTIONS; DIHYDROPYRIMIDINONES;
D O I：
10.1016/j.tet.2014.08.057
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and efficient aerobic oxidative dehydrogenation reaction method for the conversion of 2-(alkylthio)-1,4-dihydropyrimidines to 2-(alkylthio)pyrimidines using copper catalyst with no additives, such as an oxidant, acid, or base, has been developed. The reaction was successful with a wide range of 2(alkylthio)-1,4-dihydropyrimidine substrates. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码：7929 / 7935
页数：7
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