Application of factorial experimental design on the optical absorption from glucose-insulin samples in mid-infrared spectroscopy

被引:2
作者
Romo-Cardenasa, G. [1 ]
Sanchez-Lopez, J. de D. [1 ]
Luque, P. A. [1 ]
Gomez-Gutierrez, C. M. [1 ]
Nieto-Hipolito, Juan I. [1 ]
Camacho-Lopez, Santiago [2 ]
Jimenez-Cruz, Arturo [3 ]
Gastelum-Acosta, C. [1 ]
Vazquez-Briseno, M. [1 ]
Navarro-Cota, C. [1 ]
机构
[1] Univ Autonoma Baja California, Fac Ingn Arquitectura & Diseno, Ensenada 22860, Baja California, Mexico
[2] Ctr Invest Cient & Educ Super Ensenada, Dept Opt, Ensenada 22860, Baja California, Mexico
[3] Univ Autonoma Baja California, Fac Med & Psicol, Tijuana 22427, Mexico
关键词
Non-invasive blood glucose quantification; Glucose; -; insulin; Factorial experimental design; mid-IR spectroscopy;
D O I
10.1016/j.rinp.2019.102170
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
An important challenge to be addressed in the search for an optically based, non-invasive blood glucose quantification method, is related to the spectral interference between glucose and insulin in the mid-infrared region. This work proposes the use of a factorial experimental design in order to understand the optical overlapping of these compounds. The results show how in the 1100-950 cm(-1) range, glucose has a greater contribution than insulin to the absorption spectrum, without a significant effect from their interaction. These results and the use of the proposed technique could bring in interesting insights for biomedical applications.
引用
收藏
页数:3
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