Molecular Imaging of Aortic Valve Stenosis with Positron Emission Tomography

被引：3

作者：

Oostveen, Reindert F. ^{[1
]}

Kaiser, Yannick ^{[1
]}

Stroes, Erik S. G. ^{[1
]}

Verberne, Hein J. ^{[2
]}

机构：

[1] Univ Amsterdam, Dept Vasc Med, Amsterdam UMC, Amsterdam Cardiovasc Sci, NL-1105 AZ Amsterdam, Netherlands

[2] Univ Amsterdam, Dept Radiol & Nucl Med, Amsterdam UMC, NL-1105 AZ Amsterdam, Netherlands

来源：

PHARMACEUTICALS | 2022年 / 15卷 / 07期

关键词：

aortic valve stenosis; positron emission tomography; fluorodeoxyglucose; sodium fluoride; 18F-SODIUM FLUORIDE UPTAKE; ATHEROSCLEROTIC INFLAMMATION; PLAQUE INFLAMMATION; RISK-FACTORS; EARLY LESION; CALCIFICATION; PROGRESSION; THERAPY; PET; LIPOPROTEIN(A);

D O I：

10.3390/ph15070812

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Aortic valve stenosis (AVS) is an increasingly prevalent disease in our aging population. Although multiple risk factors for AVS have been elucidated, medical therapies capable of slowing down disease progression remain unavailable. Molecular imaging technologies are opening up avenues for the non-invasive assessment of disease progression, allowing the assessment of (early) medical interventions. This review will focus on the role of positron emission tomography of the aortic valve with F-18-fluorodeoxyglucose and F-18-sodium fluoride but will also shed light on novel tracers which have potential in AVS, ranging from the healthy aortic valve to end-stage valvular disease.

引用

页数：9

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