Renal manifestations of syphilis

被引:23
作者
Shettigar, Reshma [1 ]
Schollum, John [2 ]
Putt, Tracey [1 ]
Chan, Ling [3 ]
Lau, Michael [3 ]
Walker, Robert [2 ]
机构
[1] Dunedin Publ Hosp, Nephrol, Dunedin, New Zealand
[2] Univ Otago, Med, Dunedin, New Zealand
[3] Southern Community Labs, Pathol, Dunedin, New Zealand
关键词
syphilis; kidney disease; secondary membranous nephropathy; SECONDARY SYPHILIS; NEPHROTIC SYNDROME; GLOMERULONEPHRITIS; ANTIBODIES; PATIENT; MALIGNANCY; HEPATITIS;
D O I
10.1111/imj.15407
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Syphilis is a sexually transmitted disease caused by spirochaete Treponema pallidum. The incidence of syphilis is rising across the globe. It has been described in the literature as a great imitator due to the vast range of clinical manifestations that can occur in the disease. Renal manifestations are rare but a feature of secondary syphilis. It can cause glomerulopathies, tubular pathology and vasculitic lesions in the kidney. Membranous nephropathy is the most commonly reported glomerular lesion associated with syphilis. With two recent cases of secondary membranous nephropathy due to syphilis, it is timely to review the current state of knowledge, and discuss the different renal manifestation of syphilis, its pathology and treatment options.
引用
收藏
页码:1160 / 1167
页数:8
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