SAFETY AND EFFICACY OF ULTRASOUND-GUIDED HIGH-INTENSITY FOCUSED ULTRASOUND TREATMENT FOR UTERINE FIBROIDS AND ADENOMYOSIS

被引：84
作者：
Lee, Jae-Seong [1 ]
Hong, Gi-Youn [2 ]
Lee, Kye-Hwa [3 ]
Song, Jung-Hwa [4 ]
Kim, Tae-Eung [4 ]
机构：
[1] Aegisroen Obstet Gynecol Clin, Seoul, South Korea
[2] Green Cross Med Clin, Incheon, South Korea
[3] Seoul Natl Univ Hosp, Ctr Precis Med, Seoul, South Korea
[4] Catholic Univ Korea, Incheon St Marys Hosp, Coll Med, Dept Obstet & Gynecol, 56 Dongsu Ro, Incheon 21431, South Korea
来源：
ULTRASOUND IN MEDICINE AND BIOLOGY | 2019年 / 45卷 / 12期
关键词：
Uterine fibroid; Adenomyosis; High-intensity focused ultrasound ablation; Efficacy; Safety; ABLATION;
D O I：
10.1016/j.ultrasmedbio.2019.08.022
中图分类号：
O42 [声学];
学科分类号：
070206 ; 082403 ;
摘要：
The objective of this study was to assess the tolerability and efficacy of ultrasound-guided high-intensity focused ultrasound (USgHIFU) ablation using a Haifu JC Focused Ultrasound Tumor Therapeutic System (operating transducer frequency: 0.8 MHz, 300-400 W/cm(2)) under real-time ultrasound guidance (2.5- to 5.0-MHz imaging probe) for uterine fibroids and adenomyosis in 1807 patients (928 with fibroids and 889 with adenomyosis). Volume change and clinical symptom improvement after treatment were evaluated based on symptom severity scores and health-related quality of life scores using the Uterine Fibroid Symptom and Quality of Life questionnaires. At 3, 6 and 12 mo after treatment, symptom severity scores and health-related quality of life scores and reductions in volumes of uterine adenomyosis and fibroids all revealed good effects. The complication rate was 4.6% (84/1807). With supportive care, all complications resolved without any permanent adverse effects. Thus, USgHIFU is an effective, non-invasive modality for treating uterine fibroids and adenomyosis with manageable complications. (C) 2019 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
引用
收藏
页码：3214 / 3221
页数：8
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