Clear-cell carcinoma of the ovary

被引：72
|
作者：
Fujiwara, K. [1 ]
Shintani, D. [1 ]
Nishikawa, T. [1 ]
机构：
[1] Saitama Med Univ, Int Med Ctr, Dept Gynecol Oncol, Hidaka City, Japan
来源：
ANNALS OF ONCOLOGY | 2016年 / 27卷
关键词：
GYNECOLOGIC-ONCOLOGY-GROUP; ADJUVANT CHEMOTHERAPY; CANCER; ADENOCARCINOMA; IDENTIFICATION; CISPLATIN; TARGET; JAPAN;
D O I：
10.1093/annonc/mdw086
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Clear-cell carcinoma of the ovary (CCCO) is a distinct entity of epithelial ovarian cancer in terms of clinical, histopathological, or genetic features. The incidence of CCCO is different by ethnicity but the reason is not clear yet. Overall prognosis of CCCO is good because most CCCO is found in stage I. However, advanced disease is associated with a very poor prognosis and resistance to standard treatment. The same is true for recurrent disease. Therefore, genetic analysis of CCCO is important to find the right target(s) and better therapeutic approaches. Because of its rarity, international collaboration is necessary to conduct randomized clinical trials for CCCO.
引用
收藏
页码：50 / 52
页数：3
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