Fatal case of multiple recurrences of endometrial stromal sarcoma after fertility-sparing management

被引：16

作者：

Morimoto, Atsushi ^{[1
]}

Tsubamoto, Hiroshi ^{[1
]}

Inoue, Kayo ^{[1
,3
]}

Ikeda, Yuuki ^{[1
]}

Hirota, Seiichi ^{[2
]}

机构：

[1] Hyogo Coll Med, Dept Obstet & Gynecol, Nishinomiya, Hyogo 6638501, Japan

[2] Hyogo Coll Med, Dept Surg Pathol, Nishinomiya, Hyogo 6638501, Japan

[3] Meiwa Gen Hosp, Dept Obstet & Gynecol, Nishinomiya, Hyogo, Japan

来源：

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH | 2015年 / 41卷 / 01期

关键词：

c-kit; endometrial stromal sarcoma; fertility-sparing management; leuprolide; recurrence; LOW-GRADE; CONSERVATIVE MANAGEMENT; TRANSITION; PREGNANCY; UTERUS;

D O I：

10.1111/jog.12506

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Several cases of the uterus being preserved after diagnosis of endometrial stromal sarcoma (ESS) have been reported. Most of these patients were alive and did not experience relapse, but this might have reflected the short follow-up period, given the indolent recurrence of ESS. We report the first fatal case of ESS 10 years after fertility-sparing management. A specimen obtained from the last operation showed loss of estrogen receptor status and expression of c-kit without c-kit or PDGFR- gene mutations.

引用

页码：162 / 166

页数：5

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