Botulinum toxin type A in the treatment of hemifacial spasm An 11-year experience

被引：22

作者：

Barbosa, Egberto Reis ^{[1
]}

Takada, Leonel Tadao ^{[1
]}

Goncalves, Lilian Regina ^{[1
]}

Paulo do Nascimento Costa, Rose Mary ^{[1
]}

Silveira-Moriyama, Laura ^{[2
]}

Chien, Hsin Fen ^{[1
]}

机构：

[1] Univ Sao Paulo, Movement Disorders Unit, Div Neurol, Sch Med, Sao Paulo, Brazil

[2] UCL Inst Neurol, Reta Lila Weston Inst Neurol Studies, London, England

来源：

ARQUIVOS DE NEURO-PSIQUIATRIA | 2010年 / 68卷 / 04期

关键词：

botulinum toxin; hemifacial spasm; BLEPHAROSPASM; EFFICACY;

D O I：

10.1590/S0004-282X2010000400006

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In order to evaluate the long-term effect of botulinum toxin type A (BTX) in the treatment of hemifacial spasm (HFS), a retrospective analysis of patients treated at the Movement Disorders Unit of the Division of Neurology, Clinical Hospital, University of Sao Paulo, School of Medicine from 1993 to 2004 was made. A total of 808 injections with BTX were administered to 54 patients with HFS. The mean duration of improvement per application was 3.46 months and the mean rate of improvement using subjective judgement by the patient was of 83%. Adverse effects, mostly minor, were observed in 64.8% of patients at least once along the period of follow-up and the most frequent of them was orbicularis oris paralysis (38.8%). There was no decrement in response when compared the first and the last injection recorded.

引用

页码：502 / 505

页数：4

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