Exploring Phytochemicals from Himalayan Medicinal Plants as Novel Therapeutic Agents

被引:4
作者
Saini, Nidhi [1 ]
Lather, Viney [2 ]
Gahlawat, Suresh Kumar [1 ]
机构
[1] Chaudhary Devi Lal Univ, Dept Biotechnol, Sirsa 125055, India
[2] Amity Univ, Dept Pharmaceut, Noida, India
关键词
Natural products; herbal drug; complementary medicine; plant-derived drugs; drug discovery; secondary metabolites; anti-tumoral; CHEMICAL-CONSTITUENTS; ACACIA-CATECHU; ESSENTIAL OIL; ALOE-VERA; L; DATABASE; LEAVES; EXTRACT; FLOWERS; HEALTH;
D O I
10.2174/1871520621666211015141020
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Over-prescription of medicines leads to some crucial health issues like resistance, non-specificity, etc. Therefore, a human consumes various natural foods, therapeutics, and nutritional supplements to combat this problem. Various therapeutic properties of secondary metabolites, such as anticancer, anti-inflammatory, and antibacterial properties, are important in drug discovery and medicinal application. These natural products have replaced synthetic materials, resulting in a great deal of sustainability, rational use, and preservation of biodiversity. This review described the potential therapeutic applications of secondary plant metabolites found in Himalayan Indian plants. The database contains 45 plants to treat various diseases, such as cancer, inflammation, and microbial infections. Besides authorized ITIS names, it includes Hindi names, family names, and active constituents. The most important information about the molecules can be found in the hyperlinks for the active constituents. It includes structures (two-dimensional and three-dimensional), names and identifiers, chemical and physical properties, spectral information, biochemistry, literature and patents. The review also references various phytochemicals responsible for preventing COVID-19. Despite several challenges in manufacturing natural products, researchers may conduct research to produce successful medicines with few side effects.
引用
收藏
页码:1674 / 1698
页数:25
相关论文
共 173 条
  • [51] Betulin and betulinic acid: triterpenoids derivatives with a powerful biological potential
    Hordyjewska, Anna
    Ostapiuk, Aleksandra
    Horecka, Anna
    Kurzepa, Jacek
    [J]. PHYTOCHEMISTRY REVIEWS, 2019, 18 (03) : 929 - 951
  • [52] Role of Plant Derived Alkaloids and Their Mechanism in Neurodegenerative Disorders
    Hussain, Ghulam
    Rasul, Azhar
    Anwar, Haseeb
    Aziz, Nimra
    Razzaq, Aroona
    Wei, Wei
    Ali, Muhammad
    Li, Jiang
    Li, Xiaomeng
    [J]. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018, 14 (03): : 341 - 357
  • [53] Irshad M.D., 2013, NAT PRO COMM, V8, DOI [10.1177/1934578X1300800233, DOI 10.1177/1934578X1300800233]
  • [54] Jash S.K., 2014, INT J PHARM BIOMED R, V5, P51
  • [55] Jimoh SO., 2017, INT J CURR MICROBIOL, V6, P4557, DOI [10.20546/ijcmas.2017.607.476, DOI 10.20546/IJCMAS.2017.601.073]
  • [56] TINOSPORA CORDIFOLIA: A PHYTOPHARMACOLOGICAL REVIEW
    Joshi, Garish
    Kaur, Rajandeep
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2016, 7 (03): : 890 - 897
  • [57] Vasodilatory Effects and Mechanisms of Action of Bacopa monnieri Active Compounds on Rat Mesenteric Arteries
    Kamkaew, Natakorn
    Paracha, Tamkeen Urooj
    Ingkaninan, Kornkanok
    Waranuch, Neti
    Chootip, Krongkarn
    [J]. MOLECULES, 2019, 24 (12):
  • [58] PHYTOCHEMICAL CONSTITUENTS OF ALOE VERA AND THEIR MULTIFUNCTIONAL PROPERTIES: A COMPREHENSIVE REVIEW
    Kar, Sanjit Kumar
    Bera, Tushar Kanti
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2018, 9 (04): : 1416 - 1423
  • [59] Kauser A.S., 2016, EUR J PHARM MED RES, V3, P274
  • [60] Kaushik P., 2011, Chronicles of Young Scientists, V2, P71, DOI [https://doi.org/10.4103/2229-5186.82970, DOI 10.4103/2229-5186.82970]