A straightforward synthesis of phenyl boronic acid (PBA) containing BODIPY dyes: new functional and modular fluorescent tools for the tethering of the glycan domain of antibodies

被引：10

作者：

Giacomazzo, Gina Elena ^{[1
]}

Palladino, Pasquale ^{[1
]}

Gellini, Cristina ^{[1
]}

Salerno, Gianluca ^{[1
]}

Baldoneschi, Veronica ^{[1
]}

Feis, Alessandro ^{[1
]}

Scarano, Simona ^{[1
]}

Minunni, Maria ^{[1
]}

Richichi, Barbara ^{[1
]}

机构：

[1] Univ Florence, Dept Chem Ugo Schiff, Via Lastruccia 13, I-50019 Sesto Fiorentino, FI, Italy

来源：

RSC ADVANCES | 2019年 / 9卷 / 53期

关键词：

N-ACETYLNEURAMINIC ACID; CRYSTAL-STRUCTURE; DIPYRROMETHENE; PROBES; DERIVATIVES; PH; ELECTROCHEMISTRY; IMMOBILIZATION; SPECTROSCOPY; PHOTOPHYSICS;

D O I：

10.1039/c9ra07608e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report here on the efficient and straightforward synthesis of a series of modular and functional PBA-BODIPY dyes 1-4. They are an outstanding example of the efficient merge of the versatility of the 3,5-dichloro-BODIPY derivatives and the receptor-like ability of the PBA moiety. The potential bioanalytical applicability of these tools was assessed by measuring the binding to glycan chains of antibodies by a Quartz Crystal Microbalance (QCM).

引用

页码：30773 / 30777

页数：5

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