Autologous hematopoietic stem cell transplantation for very active relapsing-remitting multiple sclerosis: report of two cases

被引：21

作者：

Portaccio, E.

Amato, M. P.

Siracusa, G.

Pagliai, F.

Sorbi, S.

Guidi, S.

Bosi, A.

Saccardi, R.

机构：

[1] Univ Florence, Dept Neurol, I-50134 Florence, Italy

[2] Careggi Hosp, Bone Marrow Transplantat Unit, Florence, Italy

来源：

MULTIPLE SCLEROSIS JOURNAL | 2007年 / 13卷 / 05期

关键词：

autologous stem cell transplantation; multiple sclerosis;

D O I：

10.1177/1352458506073502

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Autologous hematopoietic stem cell transplantation (AHSCT) has been proposed as a rescue treatment in multiple sclerosis (MS) patients not responding to first- or second-line therapies. To date, most of the treated cases had a secondary progressive disease course. However, patients with high inflammatory activity, but no secondary progression of the disease, could be candidates to take greater advantage of AHSCT. In this paper, we report two cases with very active, relapsing-remitting (RR) MS, who underwent AHSCT, and obtained a dramatic resolution to disease activity.

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收藏

页码：676 / 678

页数：3

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