Immunohistochemical Expression of CD-117 (c-KIT), P-53 and Ki-67 in Adenoid Cystic Carcinoma of Palate

被引:3
作者
Bajpai, Manas [1 ]
Pardhe, Nilesh [1 ]
机构
[1] NIMS Dent Coll, Dept Oral & Maxillofacial Pathol, Jaipur, Rajasthan, India
来源
JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN | 2018年 / 28卷 / 06期
关键词
Adenoid cystic carcinoma; Palate; Immunohistochemistry; CD-117; c-KIT; P-53; Ki-67; SALIVARY-GLAND; TUMORS;
D O I
10.29271/jcpsp.2018.06.S130
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Adenoid cystic carcinoma (ACC) is a malignant tumor of salivary glands characterized histopathologically by biphasic epithelial tumor comprised of myoepithelial and ductal cells. There is a paucity of the literature regarding the immunohistochemical labelling of ACC arising in minor salivary glands. This paper reports an additional case of palatal ACC with an emphasis on its immunohistochemical staining using three different markers. Immunohistochemistry allows a better differentiation of ACC with its closest imitators, like polymorphous low grade adenocarcinoma (PLGA), considering that the latter is lesser aggressive and demands a lesser aggressive treatment approach.
引用
收藏
页码:S130 / S132
页数:3
相关论文
共 11 条
[1]   p63 immunohistochemistry in the distinction of adenoid cystic carcinoma from basaloid squamous cell carcinoma [J].
Emanuel, P ;
Wang, B ;
Wu, MX ;
Burstein, DE .
MODERN PATHOLOGY, 2005, 18 (05) :645-650
[2]  
Hosmani J., 2013, J DR NTR U HLTH SCI, V2, P142
[3]   INTRA-ORAL ADENOID CYSTIC CARCINOMA [J].
MADER, C ;
GAY, WD .
JOURNAL OF THE AMERICAN DENTAL ASSOCIATION, 1979, 99 (02) :212-214
[4]  
Marx RE, 2002, ORAL MAXILLOFACIAL P, P550
[5]  
MATSUBA HM, 1986, CANCER, V57, P519, DOI 10.1002/1097-0142(19860201)57:3<519::AID-CNCR2820570319>3.0.CO
[6]  
2-V
[7]  
Neville BW, 2009, ORAL MAXILLOFACIAL P, P495
[8]   Histologic Grading and Prognostic Biomarkers in Salivary Gland Carcinomas [J].
Seethala, Raja R. .
ADVANCES IN ANATOMIC PATHOLOGY, 2011, 18 (01) :29-45
[9]   Salivary gland tumours [J].
Speight, PM ;
Barrett, AW .
ORAL DISEASES, 2002, 8 (05) :229-240
[10]   ADENOID CYSTIC CARCINOMA [J].
STELL, PM .
CLINICAL OTOLARYNGOLOGY, 1986, 11 (04) :267-291