Dimensional Analysis of a Novel Low-Pressure Device for the Production of Size-Tunable Nanoemulsions

被引:6
作者
Souilem, Ines [1 ]
Serra, Christophe A. [1 ,2 ]
Muller, Rene [1 ,2 ]
Holl, Yves [1 ]
Bouquey, Michel [1 ,2 ]
Sutter, Christophe [3 ]
机构
[1] UPR 22 CNRS, ICS, F-67034 Strasbourg, France
[2] Univ Strasbourg UdS, Ecole Europeenne Chim Polymeres & Mat ECPM, F-67087 Strasbourg, France
[3] UMR 7515 CNRS, ICPEES, F-67087 Strasbourg, France
关键词
nanoemulsion; elongational flow; dimensional analysis; droplet size; viscosity; process parameter; model; correlation; STATIC MIXERS; POLYMERIZABLE MINIEMULSIONS; STABILITY MECHANISMS; DROP; FLOW; EMULSIFICATION; DISPERSION; FORMULATION; LIQUIDS; SYSTEMS;
D O I
10.1002/aic.14690
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
A novel low pressure device was used to generate nanoemulsions of methyl methacrylate. This device is based on a strong elongational flow known to be more efficient than the shear flow for dispersive mixing. The influence of process parameters (pressure drop number of cycles, number and size of holes) and composition parameters (monomer fraction, surfactant concentration, etc) on droplet size has shown that the average droplet size can be tailored in the range 30-200 nm by adjusting these parameters. The objective of the present paper is to find correlations that relate the obtained droplet size to the studied process and composition parameters. This model is based on a dimensional analysis using the Buckingham theorem in order to determine appropriate dimensionless numbers. This approach represents a first step for scaling up the device besides giving a set of parameters allowing to achieve a given droplet size. (c) 2014 American Institute of Chemical Engineers AIChE J, 61: 23-30, 2015
引用
收藏
页码:23 / 30
页数:8
相关论文
共 30 条
  • [1] Miniemulsion polymerization
    Asua, JM
    [J]. PROGRESS IN POLYMER SCIENCE, 2002, 27 (07) : 1283 - 1346
  • [2] A SIMPLE 2-PHASE FRICTIONAL PRESSURE-DROP CALCULATION METHOD
    BEATTIE, DRH
    WHALLEY, PB
    [J]. INTERNATIONAL JOURNAL OF MULTIPHASE FLOW, 1982, 8 (01) : 83 - 87
  • [3] DISPERSION OF VISCOUS-LIQUIDS BY TURBULENT-FLOW IN A STATIC MIXER
    BERKMAN, PD
    CALABRESE, RV
    [J]. AICHE JOURNAL, 1988, 34 (04) : 602 - 608
  • [4] Nano-emulsion formulation using spontaneous emulsification:: solvent, oil and surfactant optimisation
    Bouchemal, K
    Briançon, S
    Perrier, E
    Fessi, H
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2004, 280 (1-2) : 241 - 251
  • [5] Morphological Study of Two-Phase Polymer Blends During Compounding in a Novel Compounder on the Basis of Elongational Flows
    Bouquey, Michel
    Loux, Cyril
    Muller, Rene
    Bouchet, Gilles
    [J]. JOURNAL OF APPLIED POLYMER SCIENCE, 2011, 119 (01) : 482 - 490
  • [6] Canselier JP, 2004, GENIE PROCEDES, V2, P1
  • [7] Cicchitti A., 1960, ENERG NUCL-MILAN, V7, P407
  • [8] CONVERGING FLOW OF POLYMER MELTS
    HUANG, DC
    SHROFF, RN
    [J]. JOURNAL OF RHEOLOGY, 1981, 25 (06) : 605 - 617
  • [9] Darby R., 2001, Chemical Engineering Fluid Mechanics, Revised and Expanded
  • [10] FRICTIONAL PRESSURE DROP IN 2-PHASE FLOW .A. A COMPARISON OF EXISTING CORRELATIONS FOR PRESSURE LOSS AND HOLDUP
    DUKLER, AE
    WICKS, M
    CLEVELAND, RG
    [J]. AICHE JOURNAL, 1964, 10 (01) : 38 - 43