Zwitterionic polymerization of lactide to cyclic poly(lactide) by using N-heterocyclic carbene organocatalysts

被引：324
作者：
Culkin, Darcy A.
Jeong, Wonhee
Csihony, Szilard
Gomez, Enrique D.
Balsara, Nitash R.
Hedrick, James L.
Waymouth, Robert M. [1 ]
机构：
[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA
[2] Univ Calif Berkeley, Dept Chem Engn, Berkeley, CA 94720 USA
[3] IBM Corp, Almaden Res Ctr, San Jose, CA 95120 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 15期
关键词：
cyclization; lacticles; N-heterocyclic carbenes; ring-opening polymerization; zwitterionic polymerization;
D O I：
10.1002/anie.200604740
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Chemical Equation Presented) Closing the loop: The zwitterionic ring-opening polymerization of lactide in the presence of N-heterocyclic carbenes generates well-defined cyclic poly(lactide) (see scheme). The polymerization is rapid and produces macrocyclic polymers with high purity and exceptional control of molecular weight and polydispersity. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
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收藏
页码：2627 / 2630
页数：4
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