The Human Bocaviruses: A Review and Discussion of Their Role in Infection

被引:51
作者
Chow, Brian D. W. [2 ,3 ,4 ]
Esper, Frank P. [1 ,2 ,3 ]
机构
[1] Rainbow Babies & Childrens Hosp, Div Pediat Infect Dis, Cleveland, OH 44106 USA
[2] Case Western Reserve Univ, Cleveland, OH 44106 USA
[3] Univ Hosp Case Med Ctr, Dept Pediat, Cleveland, OH 44106 USA
[4] Univ Hosp Case Med Ctr, Dept Internal Med, Cleveland, OH 44106 USA
关键词
Human bocavirus; Human bocavirus 2; Human bocavirus 3; Viral infection; Viral gastroenteritis; Pneumonia; REAL-TIME PCR; RESPIRATORY SYNCYTIAL VIRUS; YOUNG-CHILDREN; HOSPITALIZED CHILDREN; TRACT INFECTION; ACUTE GASTROENTERITIS; HUMAN METAPNEUMOVIRUS; FREQUENT DETECTION; HUMAN CORONAVIRUS; HIGH-RISK;
D O I
10.1016/j.cll.2009.07.010
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Respiratory tract infections are a leading cause of morbidity and mortality worldwide. The human bocavirus (HBoV) is a newly recognized human parvovirus first reported in 2005. Since its discovery, this virus has been associated with upper and lower respiratory tract disease and gastroenteritis worldwide. This article is a comprehensive review of what is known about HBoV. It includes an evaluation of diagnostic modalities, symptoms occurring in affected patients, and a discussion as to whether HBoV is responsible for identified clinical manifestations. The article reviews the incidence and effect of coinfection and updates on related members (HBoV-2 and HBoV-3) recently reported. Understanding of respiratory viruses such as HBoV remains vitally important to the health of adult and pediatric patients.
引用
收藏
页码:695 / +
页数:21
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