The Human Bocaviruses: A Review and Discussion of Their Role in Infection

被引：51

作者：

Chow, Brian D. W. ^{[2
,3
,4
]}

Esper, Frank P. ^{[1
,2
,3
]}

机构：

[1] Rainbow Babies & Childrens Hosp, Div Pediat Infect Dis, Cleveland, OH 44106 USA

[2] Case Western Reserve Univ, Cleveland, OH 44106 USA

[3] Univ Hosp Case Med Ctr, Dept Pediat, Cleveland, OH 44106 USA

[4] Univ Hosp Case Med Ctr, Dept Internal Med, Cleveland, OH 44106 USA

来源：

CLINICS IN LABORATORY MEDICINE | 2009年 / 29卷 / 04期

关键词：

Human bocavirus; Human bocavirus 2; Human bocavirus 3; Viral infection; Viral gastroenteritis; Pneumonia; REAL-TIME PCR; RESPIRATORY SYNCYTIAL VIRUS; YOUNG-CHILDREN; HOSPITALIZED CHILDREN; TRACT INFECTION; ACUTE GASTROENTERITIS; HUMAN METAPNEUMOVIRUS; FREQUENT DETECTION; HUMAN CORONAVIRUS; HIGH-RISK;

D O I：

10.1016/j.cll.2009.07.010

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Respiratory tract infections are a leading cause of morbidity and mortality worldwide. The human bocavirus (HBoV) is a newly recognized human parvovirus first reported in 2005. Since its discovery, this virus has been associated with upper and lower respiratory tract disease and gastroenteritis worldwide. This article is a comprehensive review of what is known about HBoV. It includes an evaluation of diagnostic modalities, symptoms occurring in affected patients, and a discussion as to whether HBoV is responsible for identified clinical manifestations. The article reviews the incidence and effect of coinfection and updates on related members (HBoV-2 and HBoV-3) recently reported. Understanding of respiratory viruses such as HBoV remains vitally important to the health of adult and pediatric patients.

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页码：695 / +

页数：21

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