Convenient synthesis of substituted 3-alkenylpyrazolo[1,5-α]pyrimidines via Heck cross-coupling reaction

被引：24

作者：

Yin, LX ^{[1
]}

Liebscher, E ^{[1
]}

机构：

[1] Humboldt Univ, Inst Chem, D-12489 Berlin, Germany

来源：

SYNTHESIS-STUTTGART | 2004年 / 14期

关键词：

heterocycles; pyrazolo[1,5-alpha]pyrimidines; iodination; Heck reaction;

D O I：

10.1055/s-2004-831189

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-Iodopyrazolo[1,5-a]pyrimidines 3 were easily obtained by direct iodination of pyrazolo[1,5-a]pyrimidines 2 with NIS and could be transformed into a series of new substituted 3-alkenyl-pyrazolo[1,5-a]pyrimidines 5 by Heck cross-coupling.

引用

页码：2329 / 2334

页数：6

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