Degradation of cytosolic ribosomes by autophagy-related pathways

被引:25
作者
Bassham, Diane C. [1 ]
MacIntosh, Gustavo C. [2 ]
机构
[1] Iowa State Univ, Dept Genet Dev & Cell Biol, Ames, IA 50011 USA
[2] Iowa State Univ, Roy J Carver Dept Biochem Biophys & Mol Biol, Ames, IA 50011 USA
基金
美国国家科学基金会;
关键词
Autophagy; Degradation; Ribosome; rFtNA; Vacuole; ENDOPLASMIC-RETICULUM STRESS; MESSENGER-RNA DECAY; ARABIDOPSIS-THALIANA; QUALITY-CONTROL; CYSTIC LEUKOENCEPHALOPATHY; SACCHAROMYCES-CEREVISIAE; SELECTIVE AUTOPHAGY; UBIQUITIN PROTEASE; PLANT-CELLS; YEAST;
D O I
10.1016/j.plantsci.2017.05.008
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Ribosomes are essential molecular machines that require a large cellular investment, yet the mechanisms of their turnover are not well understood in any eukaryotic organism. Recent advances in Arabidopsis suggest that plants utilize selective mechanisms to transport rRNA or ribosomes to the vacuole, where rRNA is degraded and the breakdown products recycled to maintain cellular homeostasis. This review focuses on known mechanisms of rRNA turnover and explores unanswered questions on the specificity and pathways of ribosome turnover and the role of this process in maintenance of cellular homeostasis.
引用
收藏
页码:169 / 174
页数:6
相关论文
共 88 条
[11]   Proteomic characterization of evolutionarily conserved and variable proteins of arabidopsis cytosolic ribosomes [J].
Chang, IF ;
Szick-Miranda, K ;
Pan, SQ ;
Bailey-Serres, J .
PLANT PHYSIOLOGY, 2005, 137 (03) :848-862
[12]   Anthocyanin Vacuolar Inclusions Form by a Microautophagy Mechanism [J].
Chanoca, Alexandra ;
Kovinich, Nik ;
Burkel, Brian ;
Stecha, Samantha ;
Bohorquez-Restrepo, Andres ;
Ueda, Takashi ;
Eliceiri, Kevin W. ;
Grotewold, Erich ;
Otegui, Marisa S. .
PLANT CELL, 2015, 27 (09) :2545-2559
[13]   Poly(A) tail-dependent exonuclease AtRrp41p from Arabidopsis thaliana rescues 5.8 S rRNA processing and mRNA decay defects of the yeast ski6 mutant and is found in an exosome-sized complex in plant and yeast cells [J].
Chekanova, JA ;
Shaw, RJ ;
Wills, MA ;
Belostotsky, DA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (42) :33158-33166
[14]   Genome-wide high-resolution mapping of exosome substrates reveals hidden features in the Arabidopsis transcriptome [J].
Chekanova, Julia A. ;
Gregory, Brian D. ;
Reverdatto, Sergei V. ;
Chen, Huaming ;
Kumar, Ravi ;
Hooker, Tanya ;
Yazaki, Junshi ;
Li, Pinghua ;
Skiba, Nikolai ;
Peng, Qian ;
Alonso, Jose ;
Brukhin, Vladimir ;
Grossniklaus, Ueli ;
Ecker, Joseph R. ;
Belostotsky, Dmitry A. .
CELL, 2007, 131 (07) :1340-1353
[15]   A Convergence of rRNA and mRNA Quality Control Pathways Revealed by Mechanistic Analysis of Nonfunctional rRNA Decay [J].
Cole, Sarah E. ;
LaRiviere, Frederick J. ;
Merrikh, Christopher N. ;
Moore, Melissa J. .
MOLECULAR CELL, 2009, 34 (04) :440-450
[16]   The APG8/12-activating enzyme APG7 is required for proper nutrient recycling and senescence in Arabidopsis thaliana [J].
Doelling, JH ;
Walker, JM ;
Friedman, EM ;
Thompson, AR ;
Vierstra, RD .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (36) :33105-33114
[17]   Localization of RNS2 ribonuclease to the vacuole is required for its role in cellular homeostasis [J].
Floyd, Brice E. ;
Mugume, Yosia ;
Morriss, Stephanie C. ;
MacIntosh, Gustavo C. ;
Bassham, Diane C. .
PLANTA, 2017, 245 (04) :779-792
[18]   Evidence for autophagy-dependent pathways of rRNA turnover in Arabidopsis [J].
Floyd, Brice E. ;
Morriss, Stephanie C. ;
MacIntosh, Gustavo C. ;
Bassham, Diane C. .
AUTOPHAGY, 2015, 11 (12) :2199-2212
[19]   What to Eat: Evidence for Selective Autophagy in Plants [J].
Floyd, Brice E. ;
Morriss, Stephanie C. ;
MacIntosh, Gustavo C. ;
Bassham, Diane C. .
JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 2012, 54 (11) :907-920
[20]   A role for ubiquitin in the clearance of nonfunctional rRNAs [J].
Fujii, Kotaro ;
Kitabatake, Makoto ;
Sakata, Tomoko ;
Miyata, Atsumi ;
Ohno, Mutsuhito .
GENES & DEVELOPMENT, 2009, 23 (08) :963-974