Enterocin X, a Novel Two-Peptide Bacteriocin from Enterococcus faecium KU-B5, Has an Antibacterial Spectrum Entirely Different from Those of Its Component Peptides

被引：72

作者：

Hu, Chih-Bo ^{[1
]}

Malaphan, Wanna ^{[2
]}

Zendo, Takeshi ^{[1
]}

Nakayama, Jiro ^{[1
]}

Sonomoto, Kenji ^{[1
,3
]}

机构：

[1] Kyushu Univ, Grad Sch, Fac Agr,Lab Microbial Technol,Div Microbial Sci &, Dept Biosci & Biotechnol,Higashi Ku, Fukuoka 8128581, Japan

[2] Kasetsart Univ, Fac Sci, Dept Microbiol, Bangkok 10900, Thailand

[3] Kyushu Univ, Dept Funct Metab Design, Bioarchitecture Ctr, Lab Funct Food Design,Higashi Ku, Fukuoka 8128581, Japan

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2010年 / 76卷 / 13期

基金：

日本学术振兴会;

关键词：

CLASS-II BACTERIOCINS; POLYMERASE CHAIN-REACTION; LACTIC-ACID BACTERIA; IDENTIFICATION; PLANTARICIN; IMMUNITY;

D O I：

10.1128/AEM.02264-09

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Enterocin X, composed of two antibacterial peptides (X alpha and X beta), is a novel class IIb bacteriocin from Enterococcus faecium KU-B5. When combined, X alpha and X beta display variably enhanced or reduced antibacterial activity toward a panel of indicators compared to each peptide individually. In E. faecium strains that produce enterocins A and B, such as KU-B5, only one additional bacteriocin had previously been known.

引用

页码：4542 / 4545

页数：4

共 21 条

[1]

Anderssen EL, 1998, APPL ENVIRON MICROB, V64, P2269

[2] Biochemical and genetic characterization of enterocin A from Enterococcus faecium, a new antilisterial bacteriocin in the pediocin family of bacteriocins [J].