Alkaloids and citrinins from marine-derived fungus Nigrospora oryzae SCSGAF 0111

被引:27
作者
Dong, Jie-Jie [1 ,2 ]
Bao, Jie [1 ,2 ]
Zhang, Xiao-Yong [1 ]
Xu, Xin-Ya [1 ]
Nong, Xu-Hua [1 ]
Qi, Shu-Hua [1 ]
机构
[1] Chinese Acad Sci, South China Sea Inst Oceanol, RNAM Ctr Marine Microbiol, Key Lab Trop Marine Bioresources & Ecol,Guangdong, Guangzhou 510301, Guangdong, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
基金
美国国家科学基金会; 国家高技术研究发展计划(863计划);
关键词
Nigrospora oryzae; Pyrrolidinone; Indole alkaloid; Citrinin; METABOLITES; DERIVATIVES; APHIDICOLIN; ACIDS;
D O I
10.1016/j.tetlet.2014.03.060
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new pyrrolidinone, nigrospine (1), a new indole alkaloid, nigrospin A (2) and two new citrinins, nigrospins B and C (3-4) were isolated from a culture broth of the marine-derived fungal strain Nigrospora oryzae SCSGAF 0111. Their structures were determined by spectroscopic analysis, and the absolute configurations of 1 and 2 were determined by the Mosher ester technique. Compound 1 contains a rare 2,3-dihydro-benzofuran[2,3-c]2-pyrrolidone skeleton. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2749 / 2753
页数:5
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