One-pot reduction of carboxylic acids via O-acylisoureas

被引：11

作者：

Herbert, JM

Hewson, AT

Peace, JE

机构：

[1] Sanofi Res, Dept Preclin Metab & Pharmacokinet, Isotope Chem Labs, Alnwick NE66 2JH, Northd, England

[2] Sheffield Hallam Univ, Div Chem, Sheffield S1 1WB, S Yorkshire, England

[3] Sheffield Hallam Univ, Hlth Res Inst, Sheffield S1 1WB, S Yorkshire, England

来源：

SYNTHETIC COMMUNICATIONS | 1998年 / 28卷 / 05期

关键词：

D O I：

10.1080/00032719808006479

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple one-pot reduction of aliphatic carboxylic acids to primary alcohols, by treatment with dicyclohexylcarbodiimide followed by lithium borohydride, is reported. The same methodology applied to aromatic carboxylic acids is shown to give a mixture of the alcohols with N-cyclohexylcarboxamides.

引用

页码：823 / 832

页数：10

共 50 条

[41] A novel method for the one-pot conversion of carboxylic acids to N,N-dimethylamides
Kaboudin, Babak
Haghighat, Hamideh
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2012, 9 (06) : 951 - 955
[42] One-pot reductive amination of carboxylic acids: a sustainable method for primary amine synthesis
Coeck, Robin
De Vos, Dirk E.
GREEN CHEMISTRY, 2020, 22 (15) : 5105 - 5114
[43] Indium(III)-Catalyzed One-Pot Synthesis of Alkyl Cyanides from Carboxylic Acids
Moriya, Toshimitsu
Shoji, Kohei
Yoneda, Shinichiro
Ikeda, Reiko
Konakahara, Takeo
Sakai, Norio
SYNTHESIS-STUTTGART, 2013, 45 (23): : 3233 - 3238
[44] A novel method for the one-pot conversion of carboxylic acids to N,N-dimethylamides
Babak Kaboudin
Hamideh Haghighat
Journal of the Iranian Chemical Society, 2012, 9 : 951 - 955
[45] One-Pot Synthesis of 2-Substituted Benzoxazoles Directly from Carboxylic Acids
Kumar, Dinesh
Rudrawar, Santosh
Chakraborti, Asit K.
AUSTRALIAN JOURNAL OF CHEMISTRY, 2008, 61 (11) : 881 - 887
[46] Direct Hydrogenation of Nitroaromatics and One-Pot Amidation with Carboxylic Acids over Platinum Nanowires
Li, Min
Hu, Lei
Cao, Xueqin
Hong, Haiyan
Lu, Jianmei
Gu, Hongwei
CHEMISTRY-A EUROPEAN JOURNAL, 2011, 17 (09) : 2763 - 2768
[47] One-pot synthesis of α-acyloxycarbonyl compounds via oxidative decarboxylation coupling reaction of α-oxo carboxylic acids with carbonyl compounds
Chang, Li-Ming
Yuan, Gao-Qing
TETRAHEDRON, 2016, 72 (44) : 7003 - 7007
[48] TRIMETHYLAMINE-BORANE - A USEFUL REAGENT IN THE ONE-POT PREPARATION OF CARBOXYLIC ESTERS FROM CARBOXYLIC-ACIDS
TRAPANI, G
REHO, A
LATROFA, A
LISO, G
SYNTHESIS-STUTTGART, 1990, (09): : 853 - 854
[49] Acids to aldehydes in one-pot reaction
不详
CHEMICAL & ENGINEERING NEWS, 1998, 76 (46) : 30 - 30
[50] Enantioselective Synthesis of Tetrahydroquinolines via One-Pot Cascade Biomimetic Reduction
Zhao, Zi-Biao
Li, Xiang
Chen, Mu-Wang
Wu, Bo
Zhou, Yong-Gui
CHINESE JOURNAL OF CHEMISTRY, 2020, 38 (12) : 1691 - 1695

← 1 2 3 4 5 →