High fluorescence selectivity and visual detection of G-quadruplex structures by a novel dinuclear ruthenium complex

被引：76

作者：

Xu, Liang ^{[1
]}

Zhang, Dan ^{[1
]}

Huang, Jing ^{[1
]}

Deng, Minggang ^{[1
]}

Zhang, Ming ^{[1
]}

Zhou, Xiang ^{[1
,2
]}

机构：

[1] Wuhan Univ, Coll Chem & Mol Sci, Key Lab Biomed Polymers, State Key Lab Virol,Minist Educ, Wuhan 430072, Hubei, Peoples R China

[2] Lanzhou Univ, State Key Lab Appl Organ Chem, Beijing Univ, State Key Lab Nat & Biomimet Drugs, Lanzhou 730000, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 05期

关键词：

DNA STRUCTURES; BINDING; TELOMERASE; RECOGNITION; TRANSITION; ONCOGENE; PROMOTER; REGION; PROBES;

D O I：

10.1039/b918045a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel dinuclear ruthenium(II) complex with high fluorescent selectivity between DNA quadruplex structures and duplex structures was generated, and using an iodide-quenching strategy, G-quadruplex structures can be easily distinguished from duplex structures by the naked eye.

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收藏

页码：743 / 745

页数：3

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