Congenital diaphragmatic hernia: Where and what is the evidence?

被引：52

作者：

Losty, Paul D. ^{[1
]}

机构：

[1] Univ Liverpool, Alder Hey Childrens Hosp NHS Fdn Trust, Dept Paediat Surg, Liverpool L69 3BX, Merseyside, England

来源：

SEMINARS IN PEDIATRIC SURGERY | 2014年 / 23卷 / 05期

关键词：

Congenital diaphragmatic hernia; CDH; Foetal therapy; FETO; ECM; iNO; Sildenafil; Surgery; Long-term outcomes; Animal models; Genetics; TERM-FOLLOW-UP; PULMONARY HYPOPLASIA; PATCH REPAIR; IN-VITRO; LUNG; SURVIVAL; INFANTS; PREDICTION; MANAGEMENT; SURGEONS;

D O I：

10.1053/j.sempedsurg.2014.09.008

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Congenital diaphragmatic hernia (CDH) retains high mortality and morbidity due to lung hypoplasia, pulmonary hypertension and severe co-existent anomalies. This article offers a comprehensive state-of-the-art review for the paediatric surgeon whilst also describing key contributions from the basic sciences in the search to uncover the cause of the birth defect together with efforts to develop new and better therapies for CDH. (C) 2014 Elsevier Inc. All rights reserved.

引用

页码：278 / 282

页数：5

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