Bioluminescence tomography based on the phase approximation model

被引：12

作者：

Cong, W. ^{[1
]}

Wang, G. ^{[1
]}

机构：

[1] Virginia Polytech Inst & State Univ, Biomed Imaging Div, Sch Biomed Engn & Sci, Blacksburg, VA 24061 USA

来源：

JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION | 2010年 / 27卷 / 02期

关键词：

OPTICAL TOMOGRAPHY; RADIATIVE-TRANSFER; LIGHT; RECONSTRUCTION; PROPAGATION; EQUATION; TISSUES; GENE;

D O I：

10.1364/JOSAA.27.000174

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

A reconstruction method of bioluminescence sources is proposed based on a phase approximation model. Compared with the diffuse approximation, this phase approximation model more correctly predicts bioluminescence photon propagation in biological tissues, so that bioluminescence tomography can accurately locate and quantify the distribution of bioluminescence sources. The compressive sensing ( CS) technique is applied to regularize the inverse source reconstruction to enhance numerical stability and efficiency. The numerical simulation and phantom experiments demonstrate the feasibility of the proposed approach. (C) 2010 Optical Society of America

引用

页码：174 / 179

页数：6

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