Programmed Assembly of Peptide-Functionalized Gold Nanoparticles on DNA Templates

被引:38
作者
Coomber, Danielle [2 ]
Bartczak, Dorota [1 ]
Gerrard, Simon R. [2 ]
Tyas, Sarah [2 ]
Kanaras, Antonios G. [1 ]
Stulz, Eugen [2 ]
机构
[1] Univ Southampton, Sch Phys & Astron, Southampton SO17 1BJ, Hants, England
[2] Univ Southampton, Sch Chem, Southampton SO17 1BJ, Hants, England
基金
英国工程与自然科学研究理事会;
关键词
INORGANIC MATERIALS; BUILDING-BLOCKS; NANOCRYSTALS; LIGATION;
D O I
10.1021/la1023554
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We present a novel nanoparticle building block system based on the interactions between short synthetic oligonucleotides and peptides. Gold nanoparticles coated with DNA-binding peptides can be attached to self-organized oligonucleotide templates to formulate well-ordered structures of nanoparticles. By regulating the amount of DNA-binding peptide attached to the nanoparticle surface and using specifically designed oligonucleotides, the nanoparticle assembly can be controlled to form dimers, trimers, and adjustable-length nanoparticle chains as well as more complex structures.
引用
收藏
页码:13760 / 13762
页数:3
相关论文
共 26 条
[1]  
Alam MR, 2000, BIOORGAN MED CHEM, V8, P465
[2]  
ALAM MR, 1999, NUCL ACIDS S SER, V42, P173
[3]  
Baker JL, 2010, NANO LETT, V10, P195, DOI [10.1021/nl903187v, 10.1021/nl903187V]
[4]   Some recent advances in nanostructure preparation from gold and silver particles: a short topical review [J].
Brust, M ;
Kiely, CJ .
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2002, 202 (2-3) :175-186
[5]   Semisynthetic biogenic magnetosome nanoparticles for the detection of proteins and nucleic acids [J].
Ceyhan, Buelent ;
Alhorn, Petra ;
Lang, Claus ;
Schueler, Dirk ;
Niemeyer, Christof M. .
SMALL, 2006, 2 (11) :1251-1255
[6]   Peptide-Based Methods for the Preparation of Nanostructured Inorganic Materials [J].
Chen, Chun-Long ;
Rosi, Nathaniel L. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (11) :1924-1942
[7]   Enzymatic ligation creates discrete multinanoparticle building blocks for self-assembly [J].
Claridge, Shelley A. ;
Mastroianni, Alexander J. ;
Au, Yeung B. ;
Liang, Huiyang W. ;
Micheel, Christine M. ;
Frechet, Jean M. J. ;
Alivisatos, A. Paul .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (29) :9598-9605
[8]   Cluster-Assembled Materials [J].
Claridge, Shelley A. ;
Castleman, A. W., Jr. ;
Khanna, Shiv N. ;
Murray, Christopher B. ;
Sen, Ayusman ;
Weiss, Paul S. .
ACS NANO, 2009, 3 (02) :244-255
[9]   Protein- and Peptide-Directed Syntheses of Inorganic Materials [J].
Dickerson, Matthew B. ;
Sandhage, Kenneth H. ;
Naik, Rajesh R. .
CHEMICAL REVIEWS, 2008, 108 (11) :4935-4978
[10]   End-to-End Assembly of Shape-Controlled Nanocrystals via a Nanowelding Approach Mediated by Gold Domains [J].
Figuerola, Albert ;
Franchini, Isabella R. ;
Fiore, Angela ;
Mastria, Rosanna ;
Falqui, Andrea ;
Bertoni, Giovanni ;
Bals, Sara ;
Van Tendeloo, Gustaaf ;
Kudera, Stefan ;
Cingolani, Roberto ;
Manna, Liberato .
ADVANCED MATERIALS, 2009, 21 (05) :550-+