Stem Cell-Based Dental Tissue Engineering

被引:8
作者
Zivkovic, Petar [1 ]
Petrovic, Vladimir [1 ]
Najman, Stevo [1 ]
Stefanovic, Vladisav [1 ]
机构
[1] Univ Sch Med, Nish 18000, Serbia
来源
THESCIENTIFICWORLDJOURNAL | 2010年 / 10卷
关键词
tooth development; stem cells; tooth engineering; dentin-pulp complex; periodontium; HUMAN PERIODONTAL-LIGAMENT; GROWTH-FACTOR-BETA; BONE MORPHOGENETIC PROTEINS; ENAMEL MATRIX PROTEINS; TOOTH ROOT DEVELOPMENT; MARROW STROMAL CELLS; IN-VITRO; REGENERATIVE DENTISTRY; EXTRACELLULAR-MATRIX; REPARATIVE DENTIN;
D O I
10.1100/tsw.2010.81
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The development of biological and biomaterial sciences profiled tissue engineering as a new and powerful tool for biological replacement of organs. The combination of stem cells and suitable scaffolds is widely used in experiments today, in order to achieve partial or whole organ regeneration. This review focuses on the use of tissue engineering strategies in tooth regeneration, using stem cells and stem cells/scaffold constructs. Although whole tooth regeneration is still not possible, there are promising results. However, to achieve this goal, it is important to understand and further explore the mechanisms underlying tooth development. Only then will we be able to mimic the natural processes with the use of stem cells and tissue engineering techniques.
引用
收藏
页码:901 / 916
页数:16
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