The Public Access Defibrillation (PAD) Trial - Study design and rationale

被引：69

作者：

Ornato, JP ^{[1
]}

McBurnie, MA ^{[1
]}

Nichol, G ^{[1
]}

Salive, M ^{[1
]}

Weisfeldt, M ^{[1
]}

Riegel, B ^{[1
]}

Christenson, J ^{[1
]}

Terndrup, T ^{[1
]}

Daya, M ^{[1
]}

Mann, NC ^{[1
]}

Shaum, B ^{[1
]}

Brown, K ^{[1
]}

Jacobsen, K ^{[1
]}

Zalenski, R ^{[1
]}

Compton, S ^{[1
]}

Dunne, R ^{[1
]}

Swor, R ^{[1
]}

Welch, R ^{[1
]}

Mango, L ^{[1
]}

Bilicki, K ^{[1
]}

Daya, M ^{[1
]}

Gunnels, MD ^{[1
]}

Hedges, JR ^{[1
]}

Jui, J ^{[1
]}

Schmidt, T ^{[1
]}

Wittwer, L ^{[1
]}

Brooks, H ^{[1
]}

Burke, C ^{[1
]}

Griffiths, D ^{[1
]}

Becker, LB ^{[1
]}

Barry, A ^{[1
]}

Demertsidies, E ^{[1
]}

Sayre, MR ^{[1
]}

Christenson, J ^{[1
]}

Pennington, S ^{[1
]}

Holmes, A ^{[1
]}

Payne, H ^{[1
]}

Webb, R ^{[1
]}

Douglas, N ^{[1
]}

Lawson, P ^{[1
]}

Henry, MC ^{[1
]}

Johnson, S ^{[1
]}

Stapleton, ER ^{[1
]}

VanZile, J ^{[1
]}

Ottaway, M ^{[1
]}

O'Connor, RE ^{[1
]}

McGraw, P ^{[1
]}

Bollinger, M ^{[1
]}

Megargel, RE ^{[1
]}

Ehrlich, S ^{[1
]}

机构：

[1] Virginia Commonwealth Univ, Med Coll Virginia, Dept Emergency Med, Ctr Hlth, Richmond, VA 23298 USA

来源：

RESUSCITATION | 2003年 / 56卷 / 02期

关键词：

cardiopulmonary resuscitation (CPR); automated external defibrillator (AED); defibrillation; emergency medical services (EMS); ventricular fibrillation (VF); out-of-hospital cardiac arrest (OOH-CA);

D O I：

10.1016/S0300-9572(02)00442-2

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The PAD Trial is a prospective, multicenter, randomized clinical study testing whether volunteer, non-medical responders can improve survival from out-of-hospital cardiac arrest (OOH-CA) by using automated external defibrillators (AEDs). These lay volunteers, who have no traditional responsibility to respond to a medical emergency as part of their primary job description, will form part of a comprehensive, integrated community approach to the treatment of OOH-CA. The study is being conducted at 24 field centers in the United States and Canada. Approximately 1000 community units (e.g. apartment or office buildings, gated communities, sports facilities, senior centers, shopping malls, etc.) were randomized to treatment by trained laypersons who will provide either cardiopulmonary resuscitation (CPR) alone or CPR plus use of an AED, while awaiting arrival of the community's emergency medical services responders. The primary endpoint is the number of OOH-CA victims who survive to hospital discharge. Secondary endpoints include neurological status, health-related quality of life (HRQL), cost, and cost-effectiveness. Data collection will last approximately 15 months and is expected to be completed in September 2003. (C) 2003 Published by Elsevier Science Ireland Ltd.

引用

页码：135 / 147

页数：13

共 38 条

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