A reversible fluorescent Hg2+ chemosensor based on a receptor composed of a thiol atom and an alkene moiety for living cell fluorescence imaging

被引：78
作者：
Lin, Weiying [1 ]
Cao, Xiaowei [1 ]
Ding, Yundi [1 ]
Yuan, Lin [1 ]
Yu, Quanxing [1 ]
机构：
[1] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Coll Chem & Chem Engn, Changsha 410082, Hunan, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2010年 / 8卷 / 16期
关键词：
SELECTIVE FLUORESCENT; RECOGNITION PREFERENCE; AQUEOUS-SOLUTION; RHODAMINE; SENSOR; PROBE; OXYMERCURATION; SPIROLACTAM; DERIVATIVES; CONJUGATE;
D O I：
10.1039/c0ob00081g
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel reversible fluorescence turn-on chemosensor 1 for Hg2+ was constructed based on a new receptor composed of an S atom and an alkene moiety. The sensor showed a large fluorescence enhancement response (1000-fold enhancement), high selectivity, and high sensitivity with a detection limit of 27.5 nM. Significantly, the reversible sensor functioned well in the near pure aqueous medium and could be employed for Hg2+ imaging in living cells.
引用
收藏
页码：3618 / 3620
页数：3
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