A reversible fluorescent Hg2+ chemosensor based on a receptor composed of a thiol atom and an alkene moiety for living cell fluorescence imaging

被引：78
作者：
Lin, Weiying [1 ]
Cao, Xiaowei [1 ]
Ding, Yundi [1 ]
Yuan, Lin [1 ]
Yu, Quanxing [1 ]
机构：
[1] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Coll Chem & Chem Engn, Changsha 410082, Hunan, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2010年 / 8卷 / 16期
关键词：
SELECTIVE FLUORESCENT; RECOGNITION PREFERENCE; AQUEOUS-SOLUTION; RHODAMINE; SENSOR; PROBE; OXYMERCURATION; SPIROLACTAM; DERIVATIVES; CONJUGATE;
D O I：
10.1039/c0ob00081g
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel reversible fluorescence turn-on chemosensor 1 for Hg2+ was constructed based on a new receptor composed of an S atom and an alkene moiety. The sensor showed a large fluorescence enhancement response (1000-fold enhancement), high selectivity, and high sensitivity with a detection limit of 27.5 nM. Significantly, the reversible sensor functioned well in the near pure aqueous medium and could be employed for Hg2+ imaging in living cells.
引用
收藏
页码：3618 / 3620
页数：3
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共 33 条
  • [1] A general synthetic method for the formation of substituted 5-aminotetrazoles from thioureas: A strategy for diversity amplification
    Batey, RA
    Powell, DA
    [J]. ORGANIC LETTERS, 2000, 2 (20) : 3237 - 3240
  • [2] Synthesis and applications of Rhodamine derivatives as fluorescent probes
    Beija, Mariana
    Afonso, Carlos A. M.
    Martinho, Jose M. G.
    [J]. CHEMICAL SOCIETY REVIEWS, 2009, 38 (08) : 2410 - 2433
  • [3] SOLVOMERCURATION-DEMERCURATION .1. OXYMERCURATION-DEMERCURATION OF REPRESENTATIVE OLEFINS IN AN AQUEOUS SYSTEM - A CONVENIENT MILD PROCEDURE FOR MARKOVNIKOV HYDRATION OF CARBON-CARBON DOUBLE BOND
    BROWN, HC
    GEOGHEGA.PJ
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1970, 35 (06) : 1844 - &
  • [4] Highly selective chromogenic and redox or fluorescent sensors of Hg2+ in aqueous environment based on 1,4-disubstituted azines
    Caballero, A
    Martínez, R
    Lloveras, V
    Ratera, I
    Vidal-Gancedo, J
    Wurst, K
    Tárraga, A
    Molina, P
    Veciana, J
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (45) : 15666 - 15667
  • [5] Hg2+ Selective Fluorescent and Colorimetric Sensor: Its Crystal Structure and Application to Bioimaging
    Chen, Xiaoqiang
    Nam, Seong-Won
    Jou, Min Jung
    Kim, Youngmee
    Kim, Sung-Jin
    Park, Sungsu
    Yoon, Juyoung
    [J]. ORGANIC LETTERS, 2008, 10 (22) : 5235 - 5238
  • [6] ULTRASOUND IN ORGANIC-SYNTHESIS .18. SELECTIVE OXYMERCURATION VIA SONOCHEMICALLY INSITU GENERATED MERCURY SALTS
    EINHORN, J
    EINHORN, C
    LUCHE, JL
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1989, 54 (19) : 4479 - 4481
  • [7] HYDROLYSIS AND ALCOHOLYSIS OF ORTHOTHIO ESTERS
    ELLISON, RA
    WOESSNER, WD
    WILLIAMS, CC
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1974, 39 (10) : 1430 - 1432
  • [8] Synthesis of upper-rim allyl- and p-methoxyphenylazocalix[4]arenes and their efficiencies in chromogenic sensing of Hg2+ ion
    Ho, I-Ting
    Lee, Gene-Hsiang
    Chung, Wen-Sheng
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2007, 72 (07) : 2434 - 2442
  • [9] A Rhodamine-Based Hg2+ Sensor with High Selectivity and Sensitivity in Aqueous Solution: A NS2-Containing Receptor
    Huang, Junhai
    Xu, Yufang
    Qian, Xuhong
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2009, 74 (05) : 2167 - 2170
  • [10] Conformation-switched chemosensor for selective detection of Hg2+ in aqueous media
    Huang, Wei
    Wu, Da-Yu
    Duan, Chun-Ying
    [J]. INORGANIC CHEMISTRY COMMUNICATIONS, 2010, 13 (02) : 294 - 297
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