Dawn of a New Era of Targeted Antioxidant Therapies

被引：1
|
作者：
Stockwell, Brent R. [1 ,2 ]
机构：
[1] Columbia Univ, Dept Biol Sci, New York, NY 10027 USA
[2] Columbia Univ, Dept Chem, New York, NY 10027 USA
来源：
CELL CHEMICAL BIOLOGY | 2019年 / 26卷 / 11期
关键词：
D O I：
10.1016/j.chembiol.2019.11.003
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this issue of Cell Chemical Biology, Shah et al. (2019) report an in vitro, high-throughput assay that predicts the ability of compounds to suppress peroxidation of phospholipids. This approach provides a way to design and optimize targeted antioxidants that suppress specific oxidative event in cells, potentially overcoming previous failures with generic antioxidants.
引用
收藏
页码：1483 / 1485
页数：4
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