Stem Cell Therapy for Stress Urinary Incontinence

被引：10
|
作者：
Nikolavsky, Dmitriy [1 ]
Chancellor, Michael B. [1 ]
机构：
[1] William Beaumont Hosp, Dept Urol, Royal Oak, MI 48072 USA
来源：
NEUROUROLOGY AND URODYNAMICS | 2010年 / 29卷
关键词：
muscle-derived stem cells; rhabdosphincter; stress urinary incontinence; INTRINSIC SPHINCTER DEFICIENCY; MUSCLE-DERIVED CELLS; HUMAN ADIPOSE-TISSUE; LEAK POINT PRESSURE; FREE VAGINAL TAPE; RAT MODEL; PERIURETHRAL POLYTETRAFLUOROETHYLENE; CONTINENCE MECHANISMS; MYOBLAST INJECTION; NATURAL-HISTORY;
D O I：
10.1002/nau.20833
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
The rhabdosphincter at the mid urethra is critical for maintaining urinary continence. In a setting of stress urinary incontinence stem cells transplanted into the site of the rhabdosphincter may augment sphincter regeneration and also release trophic factors promoting muscle and nerve integration of this muscle. We hereby review the use of cellular therapy for SUI and our experience with the development of muscle-derived stem cells (MDSCs). Neurourol. Urodynam. 29:S36-S41, 2010. (C) 2010 Wiley-Liss, Inc.
引用
收藏
页码：S36 / S41
页数：6
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