The Etest Performed Directly on Blood Culture Bottles Is a Reliable Tool for Detection of Fluconazole-Resistant Candida albicans Isolates

被引：0
作者：
Escribano, Pilar [1 ,2 ]
Judith Marcos-Zambrano, Laura [1 ,2 ]
Gomez, Ana [1 ,2 ]
Sanchez, Carlos [1 ,2 ,3 ]
Carmen Martinez-Jimenez, M. [1 ,2 ]
Bouza, Emilio [1 ,2 ,3 ,4 ]
Guinea, Jesus [1 ,2 ,3 ,4 ]
机构：
[1] Univ Complutense Madrid, Hosp Gen Univ Gregorio Maranon, Clin Microbiol & Infect Dis Dept, Madrid, Spain
[2] Hosp Gregorio Maranon, Inst Invest Sanitaria, Madrid, Spain
[3] CIBER Enfermedades Resp CIBERES CB06 06 0058, Madrid, Spain
[4] Univ Complutense Madrid, Sch Med, Med Dept, Madrid, Spain
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2017年 / 61卷 / 07期
关键词：
Candida albicans; fluconazole; resistance; Etest; MINIMUM INHIBITORY CONCENTRATIONS; END-POINT PHENOTYPE; ANTIFUNGAL SUSCEPTIBILITY; AZOLE RESISTANCE; IN-VITRO; ERG11; MUTATIONS; RISK-FACTOR; MORTALITY; FUNGEMIA; IDENTIFICATION;
D O I：
10.1128/AAC.00400-17
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
We assessed the ability of the Etest performed directly on positive blood cultures (ETDIR) to detect fluconazole susceptibility in 6 fluconazole-resistant and 12 fluconazole-susceptible Candida albicans isolates, according to CLSI M27-A3 and EUCAST EDef 7.2 procedures. Categorical agreement between ETDIR and broth microdilution was 100% when the trays were incubated at 25 degrees C and trailing effect was ruled out. ETDIR is a reliable procedure when screening for the presence of fluconazole resistance in C. albicans.
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