Effect of tea root extract (TRE) on solid tumours induced by 3-methylcholanthrene in mice

被引：0

作者：

Chaudhuri, T ^{[1
]}

Sur, P ^{[1
]}

Gomes, A ^{[1
]}

Das, SK ^{[1
]}

Das, M ^{[1
]}

Ganguly, DK ^{[1
]}

机构：

[1] Indian Inst Chem Biol, Div Pharmacol & Expt Therapeut, Calcutta 700032, W Bengal, India

来源：

PHYTOTHERAPY RESEARCH | 1998年 / 12卷 / 01期

关键词：

tea root extract; solid tumour; antitumour activity; 3-methylanthrene (3-MC); camellia stnensis var assamica (Theaceae);

D O I：

10.1002/(SICI)1099-1573(19980201)12:1<62::AID-PTR184>3.0.CO;2-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The antitumour effect of tea plant root extract (TRE) has been evaluated against a 3-methylcholanthrene (3-MC) induced solid tumour model in ICR mice. TRE inhibited the tumur weight and the tumours were found to be non-necrotic Superoxide dismutase (SOD), a free radical scavenger, in the sera of TRE treated tumour bearing mice was found to be significantly increased while the SOD level in untreated tumour bearing animals was low. Moreover, the enhanced level of thiobarbituric acid reactive substance (TBARS) in sera of tumour bearing mice were normalized upon TRE treatment. (C) 1998 John Wiley & Sons, Ltd.

引用

页码：62 / 64

页数：3

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