?Rapid speed of response to ECT in bipolar depression: A chart review

被引：2
|
作者：
Scheepstra, K. W. F. [1 ,2 ]
van Doorn, J. B. [3 ]
Scheepens, D. S. [1 ]
de Haan, A. [1 ]
Schukking, N. [1 ]
Zantvoord, J. B. [1 ]
Lok, A. [1 ]
机构：
[1] Univ Amsterdam, Dept Psychiat, Locat AMC, Amsterdam UMC, Meibergdreef 9, NL-1105 AZ Amsterdam, Netherlands
[2] Netherlands Inst Neurosci, Neuroimmunol Res Grp, Meibergdreef 47, NL-1105 BA Amsterdam, Netherlands
[3] Univ Amsterdam, Dept Psychol Methods, Valckeniersstr 59, NL-1018 XA Amsterdam, Netherlands
来源：
JOURNAL OF PSYCHIATRIC RESEARCH | 2022年 / 147卷
关键词：
Electroconvulsive therapy; Major depressive disorder; Bipolar disorder; Depression; ELECTROCONVULSIVE-THERAPY; MAJOR DEPRESSION; REMISSION; EFFICACY; DISORDER;
D O I：
10.1016/j.jpsychires.2022.01.008
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Objective: To validate a faster speed of response to electroconvulsive therapy (ECT) for bipolar depression (BPD) compared to major depressive disorder (MDD)& nbsp;Method: Retrospective chart review on an ECT cohort in an academic hospital setting. Speed of response was defined by the number of ECT treatments needed for response or remission.& nbsp;Results: Sixty-four depressed patients were included, of whom 53 (MDD: 40, BPD: 13) could be analyzed. The bipolar group responded faster with a mean difference of 3.3 fewer ECT treatments to meet response criteria (MDD 10.4 vs. BPD 7.1, p = 0.054). When using mixed effects regression models for the response/remitter group (n = 35), a faster response for the bipolar group (AIC 252.83 vs 258.55, chi(2) =11.72, p = 0.008) was shown. Other factors, such as psychotic features or comorbidity, did not influence the speed of response.& nbsp;Conclusion: This chart review of an ECT cohort in an naturalistic academic hospital setting shows an evident and clinically relevant faster speed of response in bipolar depression.
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收藏
页码：34 / 38
页数：5
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