Successful treatment with voriconazole of invasive aspergillosis in chronic granulomatous disease

被引：54
作者：
van't Hek, LG
Verweij, PE
Weemaes, CM
van Dalen, R
Yntema, JB
Meis, JF
机构：
[1] Univ Nijmegen Hosp, Dept Med Microbiol, NL-6500 HB Nijmegen, Netherlands
[2] Univ Nijmegen Hosp, Dept Pediat Intens Care, NL-6500 HB Nijmegen, Netherlands
[3] Univ Nijmegen Hosp, Dept Pediat, NL-6500 HB Nijmegen, Netherlands
来源：
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 1998年 / 157卷 / 05期
关键词：
D O I：
10.1164/ajrccm.157.5.9709068
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
A 5-year-old boy with chronic granulomatous disease (CCD) was treated with amphotericin B for an invasive pulmonary Aspergillus nidulans infection. The infection progressed during 6 wk of treatment despite the addition of interferon-gamma (IFN-gamma), filgrastim, and transfusions with donor granulocytes. Treatment with a novel antifungal triazole, voriconazole, resulted in an excellent clinical response.
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页码：1694 / 1696
页数：3
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