Efficient regio- and stereo-selective cleavage of aziridines and epoxides using an ionic liquid as reagent and reaction medium

被引：29

作者：

Ranu, Brindaban C. ^{[1
]}

Adak, Laksmikanta ^{[1
]}

Banerjee, Subhash ^{[1
]}

机构：

[1] Indian Assoc Cultivat Sci, Dept Organ Chem, Kolkata 700032, India

来源：

CANADIAN JOURNAL OF CHEMISTRY | 2007年 / 85卷 / 05期

关键词：

aziridine; epoxide; ionic liquid; cleavage; regioselectivity; stereoselectivity;

D O I：

10.1139/V07-040

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ionic liquids, containing a variety of functionalities such as halo, azido, and thiocyano, efficiently cleave aziridines and epoxides to the corresponding products in high yields. The cleavages are regio- and stereo-selective. The reactions are complete in 1 h at 60 degrees C and do not require any other catalyst or organic solvent. Thus, a convenient synthetic route to 1,2-haloamines, 1,2-azidoamines, 1,2-thiocyanoamines, 1,2-azidoalcohols, and 1,2-thiocyanoalcohols is developed.

引用

页码：366 / 371

页数：6

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