In vitro activities of fourteen antimicrobial agents against obligately anaerobic bacteria

被引:19
作者
Schaumann, R [1 ]
Ackermann, G [1 ]
Pless, B [1 ]
Claros, MC [1 ]
Goldstein, EJC [1 ]
Rodloff, AC [1 ]
机构
[1] Univ Leipzig, Inst Med Microbiol & Epidemiol Infect Dis, D-04103 Leipzig, Germany
关键词
obligately anaerobic bacteria; antimicrobial agents; broth microdilution technique; MIC;
D O I
10.1016/S0924-8579(00)00186-2
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The in vitro activities of fourteen antimicrobial agents were tested against 292 clinical isolates of obligately anaerobic bacteria using the broth microdilution technique. Taking all strains as a group the MIC50/90 (mg/l) values were metronidazole and imipenem 0.25/1, meropenem 0.25/0.5, trovafloxacin 0.25/1, gatifloxacin and moxifloxacin 0.5/2, levofloxacin 2/16, ciprofloxacin 4/32, clindamycin 0.5/8, amoxycillin/clavulanate 1/4, doxycycline and chloramphenicol 2/4, erythromycin 4/ > 32 and penicillin G 16/ > 32. (C) 2000 Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved.
引用
收藏
页码:225 / 232
页数:8
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