Prophylactic Colectomy: Rationale, Indications, and Approach

被引：17
作者：
Kalady, Matthew F. [1 ,2 ]
Church, James M. [1 ,2 ]
机构：
[1] Cleveland Clin, Dept Colorectal Surg, Inst Digest Dis, Cleveland, OH 44195 USA
[2] Cleveland Clin, Ctr Inherited Colorectal Neoplasia, Cleveland, OH 44195 USA
来源：
JOURNAL OF SURGICAL ONCOLOGY | 2015年 / 111卷 / 01期
关键词：
hereditary colorectal cancer; prophylactic surgery; familial adenomatous polyposis; Lynch syndrome; colorectal polyposis; FAMILIAL ADENOMATOUS POLYPOSIS; POUCH-ANAL ANASTOMOSIS; QUALITY-OF-LIFE; COLORECTAL-CANCER; ILEORECTAL ANASTOMOSIS; RECTAL-CANCER; COLON-CANCER; EXTENDED COLECTOMY; RISK; CHEMOPREVENTION;
D O I：
10.1002/jso.23820
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Discerning the genetics of hereditary colorectal cancer syndromes has enabled a more individualized approach to preventing and treating colorectal cancers in affected patients and families. As these syndromes carry significant risk of colorectal cancer (nearly 100% in some cases), prophylactic colectomy is an important option for preventing cancer. This article addresses the rationale and indications for prophylactic colectomy in hereditary colorectal cancer syndromes, and provides insight into the details of surgical management. J. Surg. Oncol. 2015 111:112-117. (c) 2014 Wiley Periodicals, Inc.
引用
收藏
页码：112 / 117
页数：6
相关论文
共 43 条
[1]  
[Anonymous], BR J SURG
[2]   Meta-analysis of observational studies of ileorectal versus ileal pouch-anal anastomosis for familial adenomatous polyposis [J].
Aziz, O ;
Athanasiou, T ;
Fazio, VW ;
Nicholls, RJ ;
Darzi, AW ;
Church, J ;
Phillips, RKS ;
Tekkis, PP .
BRITISH JOURNAL OF SURGERY, 2006, 93 (04) :407-417
[3]   Ileoanal pouch neoplasia in familial adenomatous polyposis: An underestimated threat [J].
Church, J .
DISEASES OF THE COLON & RECTUM, 2005, 48 (09) :1708-1713
[4]   Risk of rectal cancer in patients after colectomy and ileorectal anastomosis for familial adenomatous polyposis - A function of available surgical options [J].
Church, J ;
Burke, C ;
McGannon, E ;
Pastean, O ;
Clark, B .
DISEASES OF THE COLON & RECTUM, 2003, 46 (09) :1175-1181
[5]  
Church J, 2001, DIS COLON RECTUM, V44, P1249, DOI 10.1007/BF02234779
[6]  
Church J, 2013, FAM CANCER, V12, pS81
[7]   Familial Adenomatous Polyposis [J].
Church, James .
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA, 2009, 18 (04) :585-+
[8]   Quality of life after prophylactic colectomy and ileorectal anastomosis in patients with familial adenomatous polyposis [J].
Church, JM ;
Fazio, VW ;
Lavery, IC ;
Oakley, JR ;
Milsom, J ;
McGannon, E .
DISEASES OF THE COLON & RECTUM, 1996, 39 (12) :1404-1408
[9]   Polishing the Crystal Ball: Knowing Genotype Improves Ability to Predict Desmoid Disease in Patients with Familial Adenomatous Polyposis [J].
Elayi, Elodie ;
Manilich, Elena ;
Church, James .
DISEASES OF THE COLON & RECTUM, 2009, 52 (10) :1762-1766
[10]   Mortality, morbidity and functional outcome after ileorectal anastomosis [J].
Elton, C ;
Makin, G ;
Hitos, K ;
Cohen, CRG .
BRITISH JOURNAL OF SURGERY, 2003, 90 (01) :59-65
12345