Advances in serum protein electrophoresis

被引:59
作者
Bossuyt, Xavier [1 ]
机构
[1] Univ Hosp Leuven, Lab Med Immunol, B-3000 Louvain, Belgium
来源
ADVANCES IN CLINICAL CHEMISTRY, VOL 42 | 2006年 / 42卷
关键词
D O I
10.1016/S0065-2423(06)42002-3
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
A major advance in serum protein electrophoresis in the last decade has been the introduction of capillary zone electrophoresis (CZE). Two dedicated automated multichannel instruments for serum protein separation by CZE in clinical laboratories are available, the Paragon CZE 2000((R)) (Beckman Coulter, CA) and the Capillarys((R)) (Sebia, France). This chapter focuses on the performance of these commercial multichannel CZE systems. Following topics are addressed: precision, comparison of CZE with gel-based methods, dysproteinemia analysis by CZE, detection and identification of monoclonal proteins by CZE, quality control, and interferences. Examples of electrophoretic patterns are given.
引用
收藏
页码:43 / 80
页数:38
相关论文
共 63 条
[1]  
Arranz-Peña ML, 2000, CLIN CHEM, V46, P736
[2]  
Bienvenu J, 1998, CLIN CHEM, V44, P599
[3]  
Blessum CR, 1999, CLIN CHEM, V45, P1313
[4]  
Bossuyt X, 1998, CLIN CHEM, V44, P760
[5]  
Bossuyt X, 1999, CLIN CHEM, V45, P129
[6]  
Bossuyt X, 1998, CLIN CHEM, V44, P944
[7]   Separation of serum proteins by automated capillary zone electrophoresis [J].
Bossuyt, X .
CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2003, 41 (06) :762-772
[8]   Automated serum protein electrophoresis by Capillarys® [J].
Bossuyt, X ;
Lissoir, B ;
Mariën, G ;
Maisin, D ;
Vunckx, J ;
Blanckaert, N ;
Wallemacq, P .
CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2003, 41 (05) :704-710
[9]   Effect of sulfamethoxazole on clinical capillary zone electrophoresis of serum proteins [J].
Bossuyt, X ;
Verhaegen, J ;
Mariën, G ;
Blanckaert, N .
CLINICAL CHEMISTRY, 2003, 49 (02) :340-341
[10]  
Bossuyt X, 2002, CLIN CHEM, V48, P204