The Evolving Landscape of Fungal Diagnostics, Current and Emerging Microbiological Approaches

被引：28
作者：
Weiss, Zoe Freeman [1 ,2 ]
Leon, Armando [1 ]
Koo, Sophia [1 ]
机构：
[1] Brigham & Womens Hosp, Div Infect Dis, Boston, MA 02115 USA
[2] Massachusetts Gen Hosp, Div Infect Dis, Boston, MA 02115 USA
来源：
JOURNAL OF FUNGI | 2021年 / 7卷 / 02期
关键词：
fungal diagnostics; mycoses; invasive candidiasis; invasive mold infections; invasive aspergillosis; mucormycosis; transplant; immunocompromised host; non-culture diagnostics; culture independent; INVASIVE PULMONARY ASPERGILLOSIS; DESORPTION IONIZATION-TIME; FLIGHT MASS-SPECTROMETRY; BRONCHOALVEOLAR LAVAGE FLUID; INTENSIVE-CARE-UNIT; GERM TUBE ANTIBODY; CANDIDA-ALBICANS; ANTIFUNGAL SUSCEPTIBILITY; PCR ASSAY; SPECIES IDENTIFICATION;
D O I：
10.3390/jof7020127
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Invasive fungal infections are increasingly recognized in immunocompromised hosts. Current diagnostic techniques are limited by low sensitivity and prolonged turnaround times. We review emerging diagnostic technologies and platforms for diagnosing the clinically invasive disease caused by Candida, Aspergillus, and Mucorales.
引用
收藏
页码：1 / 27
页数：27
相关论文
共 148 条
  • [81] Comparison of an Aspergillus Real-time Polymerase Chain Reaction Assay with Galactomannan Testing of Bronchoalvelolar Lavage Fluid for the Diagnosis of Invasive Pulmonary Aspergillosis in Lung Transplant Recipients
    Luong, Me-Linh
    Clancy, Cornelius J.
    Vadnerkar, Aniket
    Kwak, Eun Jeong
    Silveira, Fernanda P.
    Wissel, Mark C.
    Grantham, Kevin J.
    Shields, Ryan K.
    Crespo, Maria
    Pilewski, Joseph
    Toyoda, Yoshiya
    Kleiboeker, Steven B.
    Pakstis, Diana
    Reddy, Sushruth K.
    Walsh, Thomas J.
    Nguyen, M. Hong
    [J]. CLINICAL INFECTIOUS DISEASES, 2011, 52 (10) : 1218 - 1226
  • [82] MALDI-TOF MS-based drug susceptibility testing of pathogens: The example of Candida albicans and fluconazole
    Marinach, Carine
    Alanio, Alexandre
    Palous, Martine
    Kwasek, Stephanie
    Fekkar, Arnaud
    Brossas, Jean-Yves
    Brun, Sophie
    Snounou, Georges
    Hennequin, Christophe
    Sanglard, Dominique
    Datry, Annick
    Golmard, Jean-Louis
    Mazier, Dominique
    [J]. PROTEOMICS, 2009, 9 (20) : 4627 - 4631
  • [83] Marino C, 2017, FUTUR SCI OA, V3, DOI 10.4155/fsoa-2017-0030
  • [84] Urine Antigen Detection as an Aid to Diagnose Invasive Aspergillosis
    Marr, Kieren A.
    Datta, Kausik
    Mehta, Seema
    Ostrander, Darin B.
    Rock, Michelle
    Francis, Jesse
    Feldmesser, Marta
    [J]. CLINICAL INFECTIOUS DISEASES, 2018, 67 (11) : 1705 - 1711
  • [85] Profile of GenMark's ePlex® blood culture identification fungal pathogen panel
    Maubon, Daniele
    Dard, Celine
    Garnaud, Cecile
    Cornet, Muriel
    [J]. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS, 2018, 18 (02) : 119 - 132
  • [86] Serial Detection of Circulating Mucorales DNA in Invasive Mucormycosis: A Retrospective Multicenter Evaluation
    Mercier, Toine
    Reynders, Marijke
    Beuselinck, Kurt
    Guldentops, Ellen
    Maertens, Johan
    Lagrou, Katrien
    [J]. JOURNAL OF FUNGI, 2019, 5 (04)
  • [87] Lateral flow assays for diagnosing invasive pulmonary aspergillosis in adult hematology patients: A comparative multicenter study
    Mercier, Toine
    Dunbar, Albert
    de Kort, Elizabeth
    Schauwvlieghe, Alexander
    Reynders, Marijke
    Guldentops, Ellen
    Blijlevens, Nicole M. A.
    Vonk, Alieke G.
    Rijnders, Bart
    Verweij, Paul E.
    Lagrou, Katrien
    Maertens, Johan
    [J]. MEDICAL MYCOLOGY, 2020, 58 (04) : 444 - 452
  • [88] The use of mannan antigen and anti-mannan antibodies in the diagnosis of invasive candidiasis: recommendations from the Third European Conference on Infections in Leukemia
    Mikulska, Malgorzata
    Calandra, Thierry
    Sanguinetti, Maurizio
    Poulain, Daniel
    Viscoli, Claudio
    [J]. CRITICAL CARE, 2010, 14 (06):
  • [89] Early diagnosis and monitoring of mucormycosis by detection of circulating DNA in serum: retrospective analysis of 44 cases collected through the French Surveillance Network of Invasive Fungal Infections (RESSIF)
    Millon, L.
    Herbrecht, R.
    Grenouillet, F.
    Morio, F.
    Alanio, A.
    Letscher-Bru, V.
    Cassaing, S.
    Chouaki, T.
    Kauffmann-Lacroix, C.
    Poirier, P.
    Toubas, D.
    Augereau, O.
    Rocchi, S.
    Garcia-Hermoso, D.
    Bretagne, S.
    [J]. CLINICAL MICROBIOLOGY AND INFECTION, 2016, 22 (09) : 810.e1 - 810.e8
  • [90] Molecular Strategies to Diagnose Mucormycosis
    Millon, Laurence
    Scherer, Emeline
    Rocchi, Steffi
    Bellanger, Anne-Pauline
    [J]. JOURNAL OF FUNGI, 2019, 5 (01)
45678910111213