Advances in the pharmaceutical treatment options for canine osteoarthritis

被引:24
作者
Pye, C. [1 ]
Bruniges, N. [2 ]
Peffers, M. [1 ]
Comerford, E. [1 ]
机构
[1] Univ Liverpool, Fac Hlth & Life Sci, Inst Life Course & Med Sci, William Henry Duncan Bldg,6 West Derby St, Liverpool L7 8TX, Merseyside, England
[2] Univ Liverpool, Small Anim Teaching Hosp, Leahurst Campus,Chester High Rd, Neston CH64 7TE, England
关键词
MESENCHYMAL STEM-CELLS; PLATELET-RICH PLASMA; BRIEF PAIN INVENTORY; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; PROSTAGLANDIN RECEPTOR ANTAGONIST; PENTOSAN POLYSULFATE SODIUM; STROMAL-VASCULAR FRACTION; EVIDENCE-BASED MEDICINE; ARTICULAR-CARTILAGE; ADIPOSE-TISSUE;
D O I
10.1111/jsap.13495
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Canine osteoarthritis is a significant cause of pain in many dogs and can therefore compromise animal welfare. As the understanding of the biology and pain mechanisms underpinning osteoarthritis grows, so do the number of treatments available to manage it. Over the last decade, there have been a number of advances in the pharmaceutical treatment options available for dogs with osteoarthritis, as well as an increasing number of clinical trials investigating the efficacy of pre-existing treatments. This review aims to examine the current evidence behind pharmaceutical treatment options for canine osteoarthritis, including non-steroidal anti-inflammatory drugs, piprants, monoclonal antibodies, adjunctive analgesics, structure modifying osteoarthritis drugs and regenerative therapies.
引用
收藏
页码:721 / 738
页数:18
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